Aydemir, Ahmet Nadir
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Aydemir A.N Aydemir, AN A. N. Aydemir Aydemir, Ahmet Nadir. Aydemir, A. N. Aydemir, A.N. Aydemir, Nadir
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aaydemir@pau.edu.tr
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14.01. Surgical Medicine
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1NO POVERTY
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2ZERO HUNGER
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3GOOD HEALTH AND WELL-BEING
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4QUALITY EDUCATION
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5GENDER EQUALITY
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6CLEAN WATER AND SANITATION
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7AFFORDABLE AND CLEAN ENERGY
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8DECENT WORK AND ECONOMIC GROWTH
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9INDUSTRY, INNOVATION AND INFRASTRUCTURE
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10REDUCED INEQUALITIES
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11SUSTAINABLE CITIES AND COMMUNITIES
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12RESPONSIBLE CONSUMPTION AND PRODUCTION
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13CLIMATE ACTION
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14LIFE BELOW WATER
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15LIFE ON LAND
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16PEACE, JUSTICE AND STRONG INSTITUTIONS
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17PARTNERSHIPS FOR THE GOALS
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Scholarly Output
36
Articles
33
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2505/2366
Supervised MSc Theses
1
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WoS Citation Count
68
Scopus Citation Count
86
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0
WoS Citations per Publication
1.89
Scopus Citations per Publication
2.39
Open Access Source
28
Supervised Theses
1
| Journal | Count |
|---|---|
| Pamukkale Medical Journal | 5 |
| Pamukkale Tıp Dergisi | 3 |
| Joint Diseases and Related Surgery | 2 |
| Acta Ortopedica Brasileira | 2 |
| Turkish Journal of Clinics and Laboratory | 2 |
Current Page: 1 / 5
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36 results
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Now showing 1 - 10 of 36
Article Evaluation of Pathogens Isolated from Wound Infections and Their Antibiotic Susceptibility Profiles in a Wound Care Unit(J infection developing Countries, 2025-09-30) Yucens, Mehmet; Sari, Tugba; Aydemir, Nadir; Ozturk, Suna Secil; Akman, Alp; Inal, Ozan; Demirkan, FahirIntroduction: Wound infections, particularly diabetic foot infections (DFIs), are major clinical challenges, often exacerbated by polymicrobial colonization and rising antibiotic resistance. This study evaluates the pathogens isolated from DFIs in a Turkish hospital and their antibiotic susceptibility profiles to guide empirical treatment. Methodology: A retrospective study was conducted in the orthopaedic wound care unit of Pamukkale University Hospital. Data from 478 wound cultures of 136 patients treated between 11/02/2021 and 02/03/2023 were analyzed. Pathogens were identified using microbiological methods and the VITEK 2 system, with antibiotic susceptibility testing performed via the Kirby-Bauer disc diffusion method, following Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Among the 478 clinical samples, 66.9% displayed monomicrobial growth, and 32.1% were polymicrobial. Gram-negative bacteria were more prevalent, found in 85.7% of samples, with Escherichia coli (21.5%) and Pseudomonas aeruginosa (14%) being the dominant isolates. Gram-positive organisms were identified in 50.6% of cases, with Staphylococcus aureus (11.7%) as the most common, of which 8.9% were methicillin-resistant (MRSA). Multidrug-resistant (MDR) strains were detected in 320 Gram-negative isolates, including E. coli (89 isolates), P. aeruginosa (40), and Proteus spp. (50). Extended-spectrum beta-lactamase (ESBL) production was observed in 27.1% of the isolates, and carbapenem resistance in 2.3%. Notably, MDR pathogens were more frequent in patients with osteomyelitis, amputations, or HbA1c levels > 8%. Conclusions: Gram-negative bacteria, particularly E. coli and P. aeruginosa, were the predominant pathogens in DFIs in Turkey. The increasing prevalence of MDR strains necessitates careful selection of empirical antibiotics, favoring coverage of Enterobacteriaceae and P. aeruginosa over MRSA until culture results are available.Article Citation - Scopus: 1Assessment of interobserver reliability for the letournel and judet classification(Atha Comunicacao & Editora, 2024) Yucens, Mehmet; Aydemir, Ahmet Nadir; Demirkan, Ahmet FahirIntroduction: The Judet and Letournel classification is the most wide- ly used classification system for acetabular fractures. Some complex fractures couldn't be classified according to this classification. The main purpose of this study was to evaluate the reliability of the Letournel and Judet classification system for acetabular fractures. Material and methods: 10 acetabular fractures were analyzed among 17 orthopedic surgeons. The surgeons were asked to classify the fractures according to the Judet and Letournel classification. Their experience, the number of surgeries, and the incision type that the surgeon uses for the anterior part of the acetabulum were recorded. Results: The overall interobserver agreement for the Letournel classification was found to be poor, with a Kappa value of 0.287. The Kappa value for interobserver agreement was 0.224 for plain radiographs, 0.293 for 2D -CT, and 0.321 for 3D -CT scans. There was no significant difference between the incision types used by the surgeons. The highest reliability was determined among the surgeons who operate on 10-20 acetabular fractures per year, with a Kappa value of 0.309. Conclusion: This results revealed that the Judet and Letournel Judet classification is not sufficient to classify acetabular fractures because of unclassified fractures and the complex algorithm of the system. Level of Evidence III; Comparative Retrospective Study.Article Effects of Traumatic Brain Injury on Vascular Response and Fracture Healing: an Experimental Study in a Rat Model(AVES, 2025-05-28) Yucens, Mehmet; Aydemir, Ahmet Nadir; Hatip, Funda Fatma Bolukbasi; Altunay, Zeynep Mine; Mete, Guelcin Abban; Bilgen, Mehmet; Demirkan, Fahir; Demirkan, Ahmet FahirObjective: This study aimed to investigate the effects of traumatic brain injury (TBI) on vascular response and fracture healing during recovery. Methods: In this experimental animal study, a total of 63 male Wistar albino rats (200-250 g) were randomly assigned to 3 groups: TBI with tibia fracture (TBI+Fx, n = 21), tibia fracture only (Fx only, n = 21), and a control group (n = 21). Traumatic brain injury was induced in the motor cortex using a controlled impact device, followed by the tibia fracture. The severity of TBI was assessed using rotarod tests. Blood samples were collected on days 1, 7, and 21 post-fracture, while brain and tibia samples were taken on day 21 following decapitation. Levels of antidiuretic hormone (ADH) and angiotensin 1-7 (Ang 1-7) were quantified using Enzyme-linked immunosorbent assays (ELISA). Fracture healing was assessed through micro-CT and histopathological analysis. Aortic segments were evaluated for contractile response and relaxation in isolated organ baths. Results: Micro-CT analysis revealed significantly greater bone volume (BV) (P = .02) and trabecular number (P = .038) in the TBI+Fx group. Histopathological healing scores were also significantly higher in the TBI+Fx group compared to the Fx only group (P = .019). Potassium chlo-ride (KCl) induced contractile responses were greater in the Fx only group than in the TBI+Fx group (P < .05). Acetylcholine (ACh) induced relaxation was diminished in both Fx and TBI+Fx groups compared to controls (P < .01), whereas sodium nitroprusside (SNP)-induced relaxation was significantly greater in the TBI+Fx group than in the Fx only and control groups (P < .05). On day 21, arginine vasopressin (AVP) levels were significantly higher in the Fx only group compared to the TBI+Fx group (P = .034), with no significant differences observed on days 1 and 7. Plasma Ang 1-7 levels were significantly elevated in the Fx only group on day 21 compared to the TBI+Fx group (P < .05). Conclusion: Traumatic brain injury was associated with accelerated fracture healing, as evidenced by increased BV, trabecular thickness, and histopathological healing scores. Additionally, TBI appeared to modulate vascular function, possibly via mechanisms involving nitric oxide and calcium signaling. These findings suggest that neuroendocrine changes following TBI may enhance fracture healing, offering potential clinical insights for managing polytrauma patients. © 2025 Elsevier B.V., All rights reserved.Article Can the anterolateral ligament be clearly identified in an embalmed cadaver?(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019) Yucens, Mehmet; Aydemir, Ahmet Nadir; Onur, Sule; Yorukoglu, Ali Cagdas; Demirkan, Ahmet FahirIntroduction: In this study, it was aimed to determine the anterolateral ligament (ALL), especially in formalin-fixed cadaver knees using several dissection techniques. The ALL was described by Segond in 1879 as a "pearly, resistant, fibrous band" in the anterolateral aspect of the human knee. Hughston et al. described this anatomical structure as the mid-third lateral capsular ligament. Claes first described this structure as ALL. Material and Methods: The ALL was initially evaluated in six formalin-fixed cadaver knees and one fresh knee. Three different techniques were used in the formalin-fixed cadaver knees. Results: In one of the six formalin-fixed cadavers and in the fresh cadaver, the ALL was able to be explored. In the formalin-fixed cadaver knee, ALL was measured 5.5 mm distal, 3.4 mm mid, and 4.3 mm proximal. In the fresh cadaver knee, the ALL was measured 7.5 mm distal, 3.9 mm mid, and 5.4 mm proximal. Discussion and Conclusion: As a result of this study in which it was aimed to determine ALL, especially in formalin-fixed cadaver knees, it was only possible to clearly determine the ALL in one of the six formalin-fixed cadaver knees and in the fresh cadaver. In conclusion it is difficult to determine ALL in embalmed cadavers.Article Does Position Affect Reduction? Comparison of the Effects of Three Different Positions on Reduction in Intertrochanteric Femur Fracture Nailing(MDPI, 2025-05-28) Okumus, Nezir; Aydemir, Ahmet NadirBackground and Objectives: Our study aimed to retrospectively examine the routine radiographs on the first postoperative day of osteosynthesis applications performed in the supine position with the help of a traction table, in the lateral decubitus position, and in the supine position in patients with intertrochanteric fractures of the femur who had a proximal femoral nail applied. It also aimed to compare them in terms of radiology. This study investigated the effects of three different patient positions on fracture reduction, a topic rarely encountered in the literature. Materials and Methods: Patients who underwent proximal femoral nailing in three different positions-the supine, traction table, and lateral decubitus positions-due to femoral intertrochanteric fractures in two different centers were analyzed. A total of 157 patients with complete early radiographs were included in this study to evaluate the quality of postoperative reduction and fixation. Results: There was a significant difference between the traction table-assisted supine position group (mean: 25.31 mm) and both the lateral decubitus position (mean: 31.91 mm) and supine position (mean: 31.79 mm) groups in terms of the TAD (p = 0.000). Regarding the collodiaphyseal angle, the traction table-assisted supine position (mean: 130.720 degrees) and lateral decubitus position (mean: 130.290 degrees) groups showed significantly higher values than the supine position group (mean: 124.190 degrees) (p = 0.000). The average lengths of the lag and compression screws were lower in the lateral decubitus position group compared with the other groups (p = 0.000). Patients in the supine position group had smaller nail diameters and lengths (p = 0.000). When examining the Cleveland-Bosworth lag screw placements, the most frequent position was center-center, including 22 patients (31%) in the traction table-assisted supine position group, 15 patients (30.6%) in the lateral decubitus position group, and 9 patients (24.3%) in the supine position group, though the difference was not statistically significant (p = 0.203). Among the reduction criteria we investigated, the TAD on the traction table was statistically significantly closer to the targeted measurement, with an average of 25.31 mm, compared with the other two positions (p = 0.000). The collodiaphyseal angle was significantly within the target range in the traction table-assisted supine group, averaging 130.720 degrees, compared with the supine position (p = 0.000). In the traction table group, according to the modified Baumgaertner classification, 59.2% achieved a good reduction; according to the Ikuta classification, subtype N accounted for 69.4%; and according to the Cleveland-Bosworth classification, a center-center placement was present in 31% of patients. Conclusions: All three types of operation can be preferred according to the habits of the surgeon operating and the variables during the operation (the fracture type, history of orthopedic surgery, and the material components of the application phase). Accompanied by these data, we recommend the traction table operation as a priority and the lateral decubitus position operation as a second preference in compliance with the technical requirements.Article Tibia plato kırıklarında schatzker ve ao / ota sınıflandırma sistemlerine göre ortopedi ve travmatoloji asistan ve uzman hekimler arasındaki güvenirlik analizi(2019) Yücens, Mehmet; Aydemir, Ahmet NadirAMAÇ: Bu çalışmadaki amacımız Schatzker ve AO / OTAsınıflamalarının Ortopedi ve Travmatoloji uzmanları ve asistanlarıarasındaki güvenilirliği incelemektir.GEREÇ VE YÖNTEM: Çalışmaya altısı Ortopedi ve Travmatolojiasistanı, altısı ise Ortopedi ve Travmatoloji uzmanı olmak üzereoniki gözlemci katıldı. Gözlemcilerden elektronik posta yoluylagönderilen 60 tibia plato kırığı olan hastanın anteroposterior velateral radyografilerinin bulunduğu standart formları Schatzker veAO / OTA sınıflandırma sistemlerine göre sınıflamaları istendi.Bulgular: Bu çalışmada Schatzker ve AO / OTA sınıflandırmalarınagöre yapılan gözlemciler arası uyumda sadece Schatzker sınıflamasıuzman hekimler tarafından değerlendirildiğinde gözlemciler arasıuyumun orta düzeyde olduğu olduğu görülmüştür. AO / OTAsınıflamasının uzman hekimler arası, asistan hekimler arası ve tümhekimler arasında uyumunun düşük düzeyde kaldığı görülmüştür.SONUÇ: Schatzker sınıflandırma sistemi AO / OTA sınıflandırmasistemi ile karşılaştırıldığında gözlemciler arası uyumunun dahayüksek olduğu görülmektedir.Article Karpal Tünel Cerrahisi Yapılan Hastaların Demografik Özellikleri(2025-06-30) Aydemir, Ahmet; Tütüncüler, ErmanAmaç: Çalışmamızın amacı karpal tünel sendromu tanısı konularak cerrahi tedavi uygulanan hastaların demografik verilerini ortaya koymak ve sonuçlarımızı literatür eşliğinde tartışmaktır. Gereç ve Yöntemler: Karpal tünel sendromu tanısı ile ortopedi ve travmatoloji kliniğinde 2023 ve 2024 yıllarında cerrahi tedavi uygulanan hastalar geriye dönük olarak hastane bilgi sisteminden taranmıştır. Hastaların dijital dosyalarından yaşı, cinsiyeti ve sağ/sol taraf bilgileri elde edilmiştir. Bulgular: Çalışmaya 257 kadın, 75 erkek toplam 332 hasta dahil edildi. Kadın hasta sayısının erkek hasta sayından fazla olması istatiksel olarak anlamlı bulundu (p < 0,001). Hastaların ortalama yaşı 55.8 idi (yaş aralığı 19-88). Yaş gruplarına göre 5 farklı gruba ayrıldığında 46-58 yaş aralığında bulunan hasta sayısı diğer gruplara göre anlamlı olarak fazla idi (p < 0,001). Hastaların tümüne baktığımızda 185’i sağ elinden, 147’si sol elinden ameliyat oldu. Sağ elinden ameliyat olan hasta sayısının fazla olması istatiksel olarak anlamlı bulundu (p < 0,005). Sonuç: Karpal sendromu nedeniyle ameliyat olan 332 hastalık retrospektif çalışmamızda hastaların kadın cinsiyet, sağ elden operasyon olma ve orta yaş etkilenimi daha belirgindir.Article Semptomatik Talus Osteokondral Lezyonlarında Anatomik ve Demografik Bulgular(Pamukkale University, 2025-03-14) A.N., Aydemir; M., Yücens; Aydemir, Ahmet; Yucens, MehmetPurpose: Talar osteochondral defects involve damage to both the chondral surface and the underlying subchondral bone tissue. The primary etiological factors are thought to be major trauma or repetitive microtrauma. Clinically, patients often report ankle pain, swelling, and restricted joint mobility, particularly after prolonged standing or physical activity. This study aims to examine the demographic characteristics of patients who were diagnosed and treated for talar osteochondral lesions presenting with symptoms at our medical center. Materials and methods: A retrospective evaluation was conducted on patients diagnosed with osteochondral lesions of the talus, who had been examined and managed by a specialized foot and ankle surgeon within the orthopedic and traumatology department of an university hospital over the past five years. Key parameters recorded included the patients’ age, sex, the laterality of the affected ankle (right or left), and the precise anatomical location of the osteochondral lesion, distinguishing between medial and lateral involvement of the talar dome. Results: This study included a total of 42 patients, with 27 being female and 15 male. The age distribution of the study cohort spanned from 18 to 70 years, with an average age calculated at 46 years. In terms of lesion localization, 36 cases were located on the medial talus, while 6 were found on the lateral aspect. Statistical analysis revealed a significant tendency for osteochondral lesions to occur on the medial side of the talus (p=1.87x10-¹¹). When assessing the affected ankle, 24 cases involved the left ankle, while 18 were in the right ankle. However, there was no statistically significant difference in laterality (p=0.175). Conclusion: Talar osteochondral defect is a condition that affecting both chondral and subchondral tissue, appear to be more frequently located medially in symptomatic patients and tend to be more common in females. © 2025 Elsevier B.V., All rights reserved.Article Citation - WoS: 7Does computerized tomography change the treatment decision in pediatric(ACTA MEDICA BELGICA, 2019) Okay, T; Aydemir, AN; Okay, E; Topkar, OM; Gulabi, D; Erol, BThe amount of displacement in medial epicondylar fracture is one of the most important criteria for treatment decision. The displacement of medial epicondyle fractures of the humerus may be underestimated by standard AP and lateral views of elbow. The aim of the current study is to show the clinical relavance of computerized tomography (CT) for medial epicondyle fractures.Article Citation - WoS: 2Citation - Scopus: 2Do adipofascial flaps affect the mechanical properties of a repaired tendon? A biomechanical rat model study.(2019-10) Koc, M.; Yucens, M.; Aydemir, N.; Yorukoglu, A. C.; Guvenc, K.; Uzun, C.; Erdal, N.The aim of this study was to evaluate the effect of vascularized and non-vascularized fascial flaps on tendon healing, specifically the maximum strain, maximum stress, elasticity and resistance of the repaired tendon. Rats were randomly divided into 3 groups: Group 1 - primary repair; Group 2 - vascularized pedicled fascial graft; Group 3 - non-vascularized free fascial graft. The rats were euthanized after 2 weeks and 40mm-long samples were taken from the Achilles tendon and gastrocnemius muscle. To evaluate the mechanical properties of the tendons, maximum load, maximum deformation, energy stored until yield point and stiffness on the load-deformation curve were measured. Based on this mechanical testing, the best group in terms of tissue strength and quality was the primary repair group. When the samples were examined individually, the two samples with the highest breaking force after the control group were in the pedicled graft group. The worst results overall were in the free graft group. We believe that if the blood flow is preserved for the fascial flap in the pedicled graft group, the tendon's breaking force would be higher.