Comparison of photoreceptor outer segment length in diabetic and idiopathic epiretinal membranes

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Date

2015-07-17

Authors

Yuksel, K.
Karakucuk, Y.
Ozkaya, A.
Pekel, G.
Baz, O.
Alagoz, C.
Yazici, A. T.

Journal Title

Journal ISSN

Volume Title

Publisher

Nature Publishing Group

Open Access Color

BRONZE

Green Open Access

Yes

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No
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Abstract

PurposeIdiopathic and diabetic epiretinal membranes (ERMs) differ significantly in terms of macular morphology. Our aim was to compare the photoreceptor outer segment (PROS) length in diabetic and idiopathic ERMs before and after surgery.MethodsFifty-two eyes of 50 patients who underwent pars plana vitrectomy (PPV) due to idiopathic and diabetic ERMs were included in this retrospective case series. All of the patients underwent ERM and internal limiting membrane (ILM) removal. The patients had been followed up 6 months postoperatively. Spectral-domain optical coherence tomography (OCT) was used to measure the PROS length, overall PR length and central foveal thickness (CFT).ResultsThe PROS length, overall PR length, and CFT were statistically significantly lower at all the postoperative visits when compared to preoperative values in both the idiopathic and diabetic ERM groups (P<0.001). The amount of decrease in PROS and overall PR length were similar in both groups after surgery (P>0.05). There was no relation between amount of PROS length change and visual acuity gain in both groups (P>0.05).ConclusionsPostoperative change of PROS length was similar in idiopathic and diabetic ERMs. PROS length change may not be an indicator of postoperative visual acuity. © 2015 Macmillan Publishers Limited.

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Keywords

adult, aged, Article, central retinal thickness, clinical article, diabetes mellitus, epiretinal membrane, female, follow up, human, idiopathic disease, male, pars plana vitrectomy, photoreceptor outer segment, photoreceptor outer segment length, postoperative period, retina fovea, retina macula cystoid edema, retrospective study, spectral domain optical coherence tomography, very elderly, visual acuity, vitrectomy, comparative study, diabetic retinopathy, middle aged, optical coherence tomography, pathology, pathophysiology, physiology, prognosis, Aged, Aged, 80 and over, Diabetic Retinopathy, Epiretinal Membrane, Female, Humans, Male, Middle Aged, Prognosis, Retinal Photoreceptor Cell Outer Segment, Retrospective Studies, Tomography, Optical Coherence, Visual Acuity, Vitrectomy, Male, visual acuity, retrospective study, very elderly, Visual Acuity, postoperative period, Vitrectomy, middle aged, 80 and over, Tomography, comparative study, pathophysiology, Aged, 80 and over, clinical article, pars plana vitrectomy, adult, photoreceptor outer segment, epiretinal membrane, Epiretinal Membrane, Middle Aged, Prognosis, aged, diabetic retinopathy, female, spectral domain optical coherence tomography, diabetes mellitus, idiopathic disease, Female, retina macula cystoid edema, Tomography, Optical Coherence, retina fovea, vitrectomy, 610, Article, male, follow up, Humans, human, Aged, Retrospective Studies, optical coherence tomography, Diabetic Retinopathy, Retinal Photoreceptor Cell Outer Segment, Aged; Aged, 80 and over; Diabetic Retinopathy/*diagnosis/physiopathology/surgery; Epiretinal Membrane/*diagnosis/physiopathology/surgery; Female; Humans; Male; Middle Aged; Prognosis; Retinal Photoreceptor Cell Outer Segment/*pathology; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity/physiology; Vitrectomy, photoreceptor outer segment length, Optical Coherence, physiology, pathology, prognosis, central retinal thickness

Fields of Science

0301 basic medicine, 0302 clinical medicine, 03 medical and health sciences

Citation

WoS Q

Q1

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Source

Eye (Basingstoke)

Volume

29

Issue

11

Start Page

1446

End Page

1452
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