Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/10008
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dc.contributor.authorPekel, Gökhan-
dc.contributor.authorAcer, S.-
dc.contributor.authorÇetin, E.N.-
dc.contributor.authorYağcı, R.-
dc.contributor.authorKaşıkçı, A.-
dc.contributor.authorÇevik, A.-
dc.date.accessioned2019-08-16T13:09:12Z
dc.date.available2019-08-16T13:09:12Z
dc.date.issued2015-
dc.identifier.issn0165-5701-
dc.identifier.urihttps://hdl.handle.net/11499/10008-
dc.identifier.urihttps://doi.org/10.1007/s10792-014-9991-z-
dc.description.abstractThe purpose of the present study was to examine the effects of intravitreal ranibizumab on ocular pulse amplitude (OPA) and retinal vessel caliber (RVC) in wet age-related macular degeneration (AMD). Thirty-two eyes of 32 wet AMD patients were included in this case series. Three consecutive monthly injections of ranibizumab were performed. The OPA was measured with the Pascal dynamic contour tonometer. RVC measurements were taken with spectral-domain optical coherence tomography. Pre-injection mean OPA value was 2.55 ± 0.76 mmHg and post-injections mean OPA value was 2.79 ± 0.88 mmHg at the last visit (p = 0.10). Pre-injection mean arteriole and venule RVC were 96.7 ± 9.4 and 125.9 ± 8.4 µm; while post-injections arteriole and venule RVC were 96.0 ± 8.7 and 125.6 ± 8.9 µm, respectively (p > 0.05). OPA and RVC are unchanged after triple intravitreal ranibizumab injections, indicating that this treatment does not significantly alter gross retina-choroidal vasculature and hemodynamics. © 2014, Springer Science+Business Media Dordrecht.en_US
dc.language.isoenen_US
dc.publisherKluwer Academic Publishersen_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAge-related macular degenerationen_US
dc.subjectIntraocular pressureen_US
dc.subjectIntravitreal injectionen_US
dc.subjectOcular pulse amplitudeen_US
dc.subjectRanibizumaben_US
dc.subjectRetinal vessel caliberen_US
dc.subjectranibizumaben_US
dc.subjectangiogenesis inhibitoren_US
dc.subjectadulten_US
dc.subjectage related macular degenerationen_US
dc.subjectageden_US
dc.subjectarterioleen_US
dc.subjectArticleen_US
dc.subjectchoroid vascularizationen_US
dc.subjectclinical articleen_US
dc.subjectcontrolled studyen_US
dc.subjectdrug efficacyen_US
dc.subjectfemaleen_US
dc.subjecthumanen_US
dc.subjectmaleen_US
dc.subjectnon contact tonometeren_US
dc.subjectocular pulse amplitudeen_US
dc.subjectprospective studyen_US
dc.subjectretina blood flowen_US
dc.subjectretina blood vesselen_US
dc.subjectretinal vessel caliberen_US
dc.subjectspectral domain optical coherence tomographyen_US
dc.subjecttreatment durationen_US
dc.subjectvenuleen_US
dc.subjectvisual acuityen_US
dc.subjectvisual system parametersen_US
dc.subjectwet macular degenerationen_US
dc.subjectblood flowen_US
dc.subjectdrug effectsen_US
dc.subjectfluorescence angiographyen_US
dc.subjectintraocular pressureen_US
dc.subjectintravitreal drug administrationen_US
dc.subjectmiddle ageden_US
dc.subjectoculoplethysmographyen_US
dc.subjectoptical coherence tomographyen_US
dc.subjectpathologyen_US
dc.subjectpathophysiologyen_US
dc.subjectphysiologyen_US
dc.subjectpulse rateen_US
dc.subjectvery elderlyen_US
dc.subjectAgeden_US
dc.subjectAged, 80 and overen_US
dc.subjectAngiogenesis Inhibitorsen_US
dc.subjectFemaleen_US
dc.subjectFluorescein Angiographyen_US
dc.subjectHumansen_US
dc.subjectIntraocular Pressureen_US
dc.subjectIntravitreal Injectionsen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectPulseen_US
dc.subjectRegional Blood Flowen_US
dc.subjectRetinal Vesselsen_US
dc.subjectTomography, Optical Coherenceen_US
dc.subjectTonometry, Ocularen_US
dc.subjectWet Macular Degenerationen_US
dc.titleOcular pulse amplitude and retinal vessel caliber changes after intravitreal ranibizumaben_US
dc.typeArticleen_US
dc.identifier.volume35en_US
dc.identifier.issue5en_US
dc.identifier.startpage657
dc.identifier.startpage657en_US
dc.identifier.endpage662en_US
dc.identifier.doi10.1007/s10792-014-9991-z-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid25186317en_US
dc.identifier.scopus2-s2.0-84940385971en_US
dc.identifier.wosWOS:000360386500011en_US
dc.identifier.scopusqualityQ2-
dc.ownerPamukkale University-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeArticle-
crisitem.author.dept14.01. Surgical Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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