Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/10067
Title: | Posterior pole asymmetry analysis and retinal thickness measurements in young relatives of glaucoma patients | Authors: | Pekel, Gökhan Acer, S. Ya?ci, R. Kaya, H. Özbakiş, F. Bahar, A. Çetin, E.N. |
Keywords: | Ganglion cell complex Posterior pole asymmetry analysis Primary open-angle glaucoma Retinal arteriolar caliber Retinal thickness adolescent adult Article comparative study controlled study cross-sectional study eye examination female first degree relative human macular thickness major clinical study male open angle glaucoma retinal nerve fiber layer thickness retinal thickness second degree relative spectral domain optical coherence tomography case control study corneal pachymetry glaucoma intraocular pressure optic disk optical coherence tomography pathology pathophysiology procedures refraction error retina retina macula lutea Adult Case-Control Studies Corneal Pachymetry Female Glaucoma Humans Intraocular Pressure Macula Lutea Male Optic Disk Refractive Errors Retina Tomography, Optical Coherence |
Publisher: | Elsevier (Singapore) Pte Ltd | Abstract: | The presence of a family history of glaucoma is a known risk factor for primary open-angle glaucoma (POAG) in middle-aged and older individuals. In this study, our aim was to demonstrate possible early glaucomatous alterations in young first- and second-degree relatives of POAG patients by spectral-domain optical coherence tomography. A total of 104 participants (52 relatives of POAG patients and 52 healthy individuals) were recruited in this cross-sectional study. All the participants were between 17 years and 45 years of age. All eyes underwent testing with spectral-domain optical coherence tomography. Peripapillary retinal nerve fiber layer thickness, hemifield macular thickness, macular ganglion cell complex thickness, posterior pole asymmetry analysis, and retinal arteriolar caliber measurements were taken for comparison between the study and control groups. The mean peripapillary retinal nerve fiber layer thickness was 104.9 ± 8.8 µm in the study group and 105.6 ± 7.4 µm in the control group (p = 0.68). Although whole macular thickness measurements were higher in the control group when compared with the study group (p = 0.008), the macular ganglion cell complex thickness was similar in both groups (p = 0.87). The posterior pole asymmetry analysis revealed no statistically significant difference between the groups in the aspect of consecutive black squares (p = 0.79). The mean retinal arteriolar caliber was 85.9 ± 4.8 µm in the study group and 86.0 ± 5.0 µm in the control group (p = 0.90). In conclusion, young relatives of POAG patients do not show characteristic glaucomatous damage when compared with the controls. © 2015, Kaohsiung Medical University. Published by Elsevier Taiwan LLC. All rights reserved. | URI: | https://hdl.handle.net/11499/10067 https://doi.org/10.1016/j.kjms.2015.06.001 |
ISSN: | 1607-551X |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
File | Size | Format | |
---|---|---|---|
Posterior pole.pdf | 775.93 kB | Adobe PDF | View/Open |
CORE Recommender
SCOPUSTM
Citations
11
checked on Aug 17, 2024
WEB OF SCIENCETM
Citations
10
checked on Aug 9, 2024
Page view(s)
36
checked on Aug 24, 2024
Download(s)
14
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.