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https://hdl.handle.net/11499/10142
Title: | Platelet function parameters in management of hepatic hydatid disease: A case-controlled study | Authors: | Dinc, B. Düşen, Serdar. Ay, N. Dinc, S.E. Mayir, B. Gunduz, U.R. Musri, O.C. |
Keywords: | Disease management Hepatic hydatid cysts Platelet function test adult aged Article blood clotting parameters case control study controlled study eosinophil female hematocrit human liver hydatid cyst major clinical study male platelet distribution width postoperative period preoperative care retrospective study sensitivity and specificity thrombocyte count thrombocyte function thrombocyte function and characteristics thrombocyte volume Moroccan pepper virus |
Publisher: | E-Century Publishing Corporation | Abstract: | Aim: To evaluate platelet function in patients with a history of surgical treatment for hepatic hydatid disease (HD). Methods: This retrospective case-controlled study was performed in a state hospital in Turkey from January 2009 to November 2013. The patients were divided into two groups: those evaluated in the preoperative period (Group 1) and those evaluated in the postoperative period (Group 2). The patient groups were compared with a control group (Group 3). All three groups were evaluated using laboratory records from day 1 of the preoperative period and day 30 of the postoperative period. The haematocrit level (HTC), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and percentage of eosinophils (EOS) were compared among the groups. Results: Fifty-three patients who had undergone surgical treatment of hepatic HD and 55 healthy controls were included in the study. The mean follow-up time for all patients was 45 (14-70) months. The patients comprised 33 (62%) females and 20 (38%) males. The control group comprised 37 (67%) females and 18 (33%) males. The median age of the patients was 48 (19-78) years, while that of the control group was 42 (16-64) years. No significant differences in the HTC, PLT, or EOS were present among the groups. The MPV and PDW indicated that platelet function was significantly different between Group 1 and Groups 2 and 3. Additionally, nine patients had undergone previous surgical treatment for HD. In a separate long-term follow-up, these patients exhibited no statistically significant differences in MPV or PDW between the preoperative and postoperative periods. Conclusions: MPV and PDW can be used in the initial follow-up of patients with hepatic HD, but have limited use in long-term follow-up. © 2015, Int J Clin Exp Med. All rights reserved. | URI: | https://hdl.handle.net/11499/10142 | ISSN: | 1940-5901 |
Appears in Collections: | Fen-Edebiyat Fakültesi Koleksiyonu PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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