Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/10311
Title: Ketamine may be related to minor troponin elevations in children undergoing minor procedures in the ED
Authors: Serinken, Mustafa
Eken, C.
Keywords: ketamine
troponin
anesthetic agent
troponin T
Article
child
childhood injury
clinical article
diastolic blood pressure
electrocardiogram
emergency ward
female
follow up
heart muscle injury
human
male
minor surgery
observational study
outcome assessment
priority journal
pulse rate
QT dispersion
QT interval
QTc interval
sedation
systolic blood pressure
blood
conscious sedation
electrocardiography
emergency health service
Facial Injuries
Hand Injuries
heart muscle ischemia
infant
preschool child
Anesthetics, Dissociative
Child, Preschool
Conscious Sedation
Electrocardiography
Emergency Service, Hospital
Humans
Infant
Ketamine
Myocardial Ischemia
Troponin T
Publisher: W.B. Saunders
Abstract: Objective Ketamine is a dissociative anesthetic agent that has an increased frequency of usage in the last years particularly in emergency departments. In the present study, we aimed to determine whether ketamine is related to myocardial injury in children undergoing minor procedures. Method Children younger than 18 years undergoing procedural sedation secondary to minor trauma composed the study population. Patients were administered ketamine with a dose of 1.5 mg/kg via intravenous route. QT interval was measured by Bazett's formula, and QT dispersion was determined by taking the average of 3 different QT intervals. High-sensitive troponin levels were measured before and 3 hours after the ketamine administration. Results A total of 30 patients were included into the study. Study subjects had a median age of 2 years (interquartile range, 1-4 years). There were 2 patients among the study patients who had troponin elevations 3 hours after the ketamine administrations. High-sensitive troponin levels of these 2 at the time of preketamine, 3, 5, and 24 hours after the ketamine administration were as follows: 5, 29, 15, and 5 ng/L and 3, 44, 41, and 4 ng/L, respectively. There was no difference before and after the ketamine administration for the corrected QT intervals and QT dispersions. Conclusion Ketamine may be related to minor troponin elevations in children undergoing procedural sedation without a permanent cardiac dysfunction. © 2015 Elsevier Inc.
URI: https://hdl.handle.net/11499/10311
https://doi.org/10.1016/j.ajem.2015.03.061
ISSN: 0735-6757
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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