Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/10358
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dc.contributor.authorIsik-Balci, Yasemin-
dc.contributor.authorTancer-Elci, H.-
dc.contributor.authorBor-Kucukatay, Melek-
dc.contributor.authorKılıç-Erkek, Özgen-
dc.contributor.authorKılıç, Emine Toprak-
dc.contributor.authorŞenol, Hande-
dc.contributor.authorRota, Simin-
dc.date.accessioned2019-08-16T13:16:38Z-
dc.date.available2019-08-16T13:16:38Z-
dc.date.issued2015-
dc.identifier.issn1386-0291-
dc.identifier.urihttps://hdl.handle.net/11499/10358-
dc.identifier.urihttps://doi.org/10.3233/CH-141811-
dc.description.abstractOBJECTIVE:We aimed to investigate the effects of iron deficiency anemia (IDA) and vitamin B12 deficiency coexisting with IDA which is called as mixed anemia (MA) on hemorheological parameters, to compare them with each other and healthy controls, and to assess the changes in hemorheological parameters after treatment. MATERIALS AND METHODS: 32 IDA patients (mean age:6.3±5.3 years), 30 MA patients (mean age:7.2±5.4 years), and 31 healthy controls (mean age:7.1±5.2 years) were enrolled. Erythrocyte deformability and aggregation were determined by an ectacytometer, plasma and whole blood viscosities by a cone-plate rotational viscometer. Differences between IDA and MA, and healthy controls were compared. Hemorheological parameters were repeated in the patient groups after treatment and compared with the initial results. RESULTS: In both of the patient groups, erythrocyte deformability, whole blood and plasma viscosities were found to be significantly decreased before treatment, compared with the controls. After treatment these parameters were found to be increased significantly. There were no significant differences in these parameters between the IDA and MA group. Additionally, no statistically significant alteration was found in erythrocyte aggregation measurements of both patient groups. CONCLUSION: This study indicates that IDA andMAhave similar effects on hemorheological parameters. When vitamin B12 deficiency accompanies IDA which is called as MA, no further alterations occur in hemorheological parameters. The adequate treatment of these anemias not only corrects the hematological parameters, but also by helping to normalize the hemorheological parameters, may contribute to the regulation of microvascular perfusion. © 2015 - IOS Press and the authors.en_US
dc.language.isoenen_US
dc.publisherIOS Pressen_US
dc.relation.ispartofClinical Hemorheology and Microcirculationen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecterythrocyte aggregationen_US
dc.subjecterythrocyte deformabilityen_US
dc.subjectIron deficiency anemiaen_US
dc.subjectmixed anemiaen_US
dc.subjectviscosityen_US
dc.subjectcyanocobalaminen_US
dc.subjectferritinen_US
dc.subjecthemoglobinen_US
dc.subjectironen_US
dc.subjecttransferrinen_US
dc.subjectadolescenten_US
dc.subjectArticleen_US
dc.subjectblood rheologyen_US
dc.subjectblood viscosityen_US
dc.subjectchilden_US
dc.subjectcontrolled studyen_US
dc.subjectcyanocobalamin deficiencyen_US
dc.subjecterythrocyte counten_US
dc.subjectfemaleen_US
dc.subjectfollow upen_US
dc.subjecthematocriten_US
dc.subjecthumanen_US
dc.subjectinfanten_US
dc.subjectiron deficiency anemiaen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectmean corpuscular volumeen_US
dc.subjectplasma viscosityen_US
dc.subjectreticulocyte counten_US
dc.subjectAnemia, Iron-Deficiencyen_US
dc.subjectblooden_US
dc.subjectChilden_US
dc.subjectErythrocyte Deformabilityen_US
dc.subjectFemaleen_US
dc.subjectFollow-Up Studiesen_US
dc.subjectHemorheologyen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.titleInvestigation of hemorheological parameters at the diagnosis and follow up of children with iron deficiency anemia and mixed anemiaen_US
dc.typeArticleen_US
dc.identifier.volume60en_US
dc.identifier.issue2en_US
dc.identifier.startpage179-
dc.identifier.startpage179en_US
dc.identifier.endpage189en_US
dc.identifier.doi10.3233/CH-141811-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid24448733en_US
dc.identifier.scopus2-s2.0-84938078190en_US
dc.identifier.wosWOS:000358727800002en_US
dc.identifier.scopusqualityQ2-
dc.ownerPamukkale University-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeArticle-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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