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https://hdl.handle.net/11499/10368
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kördikanlioğlu, Burcu | - |
dc.contributor.author | Şimşek, Ömer | - |
dc.contributor.author | Saris, P.E.J. | - |
dc.date.accessioned | 2019-08-16T13:16:51Z | |
dc.date.available | 2019-08-16T13:16:51Z | |
dc.date.issued | 2015 | - |
dc.identifier.issn | 8756-7938 | - |
dc.identifier.uri | https://hdl.handle.net/11499/10368 | - |
dc.identifier.uri | https://doi.org/10.1002/btpr.2075 | - |
dc.description.abstract | In this study, nisin production of Lactococcus lactis N8 was optimized by independent variables of glucose, hemin and oxygen concentrations in fed-batch fermentation in which respiration of cells was stimulated with hemin. Response surface model was able to explain the changes of the nisin production of L. lactis N8 in fed-batch fermentation system with high fidelity (R2 98%) and insignificant lack of fit. Accordingly, the equation developed indicated the optimum parameters for glucose, hemin, and dissolved oxygen were 8 g L-1 h-1, 3 µg mL-1 and 40%, respectively. While 1711 IU mL-1 nisin was produced by L. lactis N8 in control fed-batch fermentation, 5410 IU mL-1 nisin production was achieved within the relevant optimum parameters where the respiration of cell was stimulated with hemin. Accordingly, nisin production was enhanced 3.1 fold in fed-batch fermentation using hemin. In conclusion the nisin production of L. lactis N8 was enhanced extensively as a result of increasing the biomass by stimulating the cell respiration with adding the hemin in the fed-batch fermentation. © 2015 American Institute of Chemical Engineers. | en_US |
dc.language.iso | en | en_US |
dc.publisher | John Wiley and Sons Inc. | en_US |
dc.relation.ispartof | Biotechnology Progress | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Fed-batch fermentation | en_US |
dc.subject | Hemin | en_US |
dc.subject | L. lactis | en_US |
dc.subject | Nisin | en_US |
dc.subject | Respiration | en_US |
dc.subject | Antibiotics | en_US |
dc.subject | Cells | en_US |
dc.subject | Cytology | en_US |
dc.subject | Dissolved oxygen | en_US |
dc.subject | Glucose | en_US |
dc.subject | Oxygen | en_US |
dc.subject | Fermentation | en_US |
dc.subject | Lactococcus lactis | en_US |
dc.subject | acetic acid | en_US |
dc.subject | culture medium | en_US |
dc.subject | glucose | en_US |
dc.subject | hemin | en_US |
dc.subject | lactic acid | en_US |
dc.subject | nisin | en_US |
dc.subject | oxygen | en_US |
dc.subject | biomass | en_US |
dc.subject | biosynthesis | en_US |
dc.subject | chemistry | en_US |
dc.subject | fermentation | en_US |
dc.subject | metabolism | en_US |
dc.subject | Micrococcus luteus | en_US |
dc.subject | pH | en_US |
dc.subject | Acetic Acid | en_US |
dc.subject | Biomass | en_US |
dc.subject | Culture Media | en_US |
dc.subject | Hydrogen-Ion Concentration | en_US |
dc.subject | Lactic Acid | en_US |
dc.title | Nisin production of Lactococcus lactis N8 with hemin-stimulated cell respiration in fed-batch fermentation system | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 31 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 678 | |
dc.identifier.startpage | 678 | en_US |
dc.identifier.endpage | 685 | en_US |
dc.identifier.doi | 10.1002/btpr.2075 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 25826783 | en_US |
dc.identifier.scopus | 2-s2.0-84931565788 | en_US |
dc.identifier.wos | WOS:000356670700007 | en_US |
dc.identifier.scopusquality | Q2 | - |
dc.owner | Pamukkale University | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 10.05. Food Engineering | - |
Appears in Collections: | Mühendislik Fakültesi Koleksiyonu PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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