Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/10582
Title: Clinical and echocardiographic evaluation of our patients with myopericarditis
Authors: Gürses, Dolunay Karaduman
Oğuz, Merve
Yilmaz, M.
Keywords: Child
Myocarditis
Myopericarditis
brain natriuretic peptide
C reactive protein
creatine kinase
doxazosin
ibuprofen
immunoglobulin
immunoglobulin M
troponin T
venom
Adenoviridae
adolescent
Article
cardiovascular magnetic resonance
child
clinical article
creatine kinase blood level
echocardiography
electrocardiography
fever
follow up
heart ejection fraction
heart failure
hospitalization
human
immunoglobulin blood level
infant
injection
leukocyte count
multiplex polymerase chain reaction
myocardial perfusion imaging
myocarditis
myopericarditis
pericardial effusion
pericarditis
protein blood level
respiratory distress
retrospective study
Rhinovirus
sinus tachycardia
ST segment
thorax pain
toxic myocarditis
upper respiratory tract infection
Publisher: Ortadog u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.
Abstract: Objective: Chest pain, shortness of breath, increased cardiac biochemical markers and electrocardiographic changes suggest myocarditis in the pediatric age group. We aimed to evaluate our patients with myopericarditis, retrospectively. Material and Methods: Eighteen patients who were diagnosed with myopericarditis between January 2014-December 2017 were evaluated. Results: The age of the patients ranged from 5 months to 17 years (12.8±5). Complaints were chest pain in 16 (88%) patients, fever in 1 patient, respiratory distress and reduction in effort capacity in 1 patient. Twelve patients had upper respiratory tract infection, and one patient had a scorpion injection. The number of white cells was 10045±2706/mm 3 (5900-14580); C-reactive protein was 5.3±6.3 mg/dL (0.01-19). Cardiac enzymes were higher in all patients. The mean creatin kinase myocardial band level was 36.2±11.2 ng/mL (0.8-167) and the mean troponin T was 0.61±0.15 ng/mL (0.051-2.65). The mean level of pro-B type natriuretic peptide from seven patients due to heart failure was 5.122±2.851 pg/mL (110-20.286). Cytomegalovirusimmunglobulin M in one patient and Epstein-Barr virus-immunglobulin M in two patients were positive. Rhinovirus in 5 patients and Adenovirus in 3 patients were detected in the multiplex polymerase chain reaction respiratory tract panel. Electrocardiographic (ECG) evaluation showed sinus tachycardia in 9 patients, ST-T changes in chest leads in 11 patients, and voltage drop in 6 patients. The mean ejection fraction was 68.2±2.9 (35-88). Ten patients had pericardial effusion. Three patients underwent myocardial perfusion scintigraphy and two patients underwent cardiac magnetic resonance imaging. Ten patients were treated with ibuprofen (30 mg/kg/day) and intravenous immunoglobulin (2 g/kg/24 h) was given to twelve patients who showed elevated levels of troponin T in the follow-up. A case of toxic myocarditis developed after scorpion insertion was treated with doxazosin and antivenom. On follow-up, cardiac enzymes remained high on average 6±3.1 (2-13) days. The mean duration of hospitalization was 6±3.6 (2-16) days. Conclusion: Patients with elevated cardiac enzymes and/or ECG changes should be evaluated for myocarditis. © 2018 by Türkiye Klinikleri.
URI: https://hdl.handle.net/11499/10582
https://doi.org/10.5336/pediatr.2018-62223
ISSN: 1300-0381
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

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