Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/11032
Title: | Cutaneous findings of crimean-congo hemorrhagic fever: A study of 269 cases | Authors: | Duygu, F. Sarı, Tuğba Gunal, O. Barut, S. Atay, A. Aytekin, F. |
Keywords: | alanine aminotransferase aspartate aminotransferase creatine kinase immunoglobulin G immunoglobulin M lactate dehydrogenase virus RNA adult arthralgia Article cohort analysis controlled study Crimean Congo hemorrhagic fever disease course ecchymosis enzyme linked immunosorbent assay female fever headache human leukocyte count leukopenia maculopapular rash major clinical study male mortality rate myalgia nausea and vomiting partial thromboplastin time petechia platelet count polymerase chain reaction prospective study prothrombin time rash reverse transcription polymerase chain reaction risk factor sequence analysis thrombocytopenia adolescent aged middle aged mortality pathology skin survival analysis young adult Adolescent Adult Aged Ecchymosis Exanthema Female Hemorrhagic Fever, Crimean Humans Male Middle Aged Prospective Studies Skin Survival Analysis Young Adult |
Publisher: | National Institute of Health | Abstract: | Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic viral disease. We aimed to investigate the cutaneous manifestations of CCHF and reveal their associations with fatality. Two hundred and sixty-nine patients diagnosed with CCHF were assessed. Skin findings were observed in 170 (63.2%) patients. A facial rash was the most common cutaneous finding (n = 82, 30.5%). In severe cases, hemorrhagic cutaneous manifestations (petechiae and ecchymoses) were recognized. A statistically significant correlation was obtained between cutaneous manifestations and fatality, and it was determined that there was a strong positive correlation between fatality and ecchymosis (r = 567, p < 0.001). In addition, a logistic regression analysis was performed, and death occurred 4.69 times more in those with skin signs than in those without. We hypothesize that CCHF patients with ecchymosis are at the highest risk and that cutaneous findings can contribute to the prognosis of CCHF. © 2018, National Institute of Health. All rights reserved. | URI: | https://hdl.handle.net/11499/11032 https://doi.org/10.7883/yoken.JJID.2018.005 |
ISSN: | 1344-6304 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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