Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/23773
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dc.contributor.authorTopsakal, Şenay-
dc.contributor.authorOzmen, O-
dc.contributor.authorCicek, E-
dc.contributor.authorComlekci, S-
dc.date.accessioned2019-08-20T06:55:52Z
dc.date.available2019-08-20T06:55:52Z
dc.date.issued2017-
dc.identifier.issn1687-8507-
dc.identifier.urihttps://hdl.handle.net/11499/23773-
dc.identifier.urihttps://doi.org/10.1016/j.jrras.2017.04.009-
dc.description.abstractThe aim of this study was to investigate the effects of electromagnetic radiation (EMR) on the pancreas tissue of young rats and the ameliorative effect of Gallic acid (GA). Six-week-old, 48 male rats were equally divided into four groups: Sham group, EMR group (2.45 GHz), EMR (2.45 GHz)+GA group (30 mg/kg/daily) orally and GA group (30 mg/kg/daily). After 30 days, serum and pancreatic tissue samples were harvested for biochemical, histopathological and immunohistochemical analysis. Serum amylase, lipase, glucose, and tissue malondialdehyde, total oxidant status and oxidative stress index were increased, whereas total antioxidant status decreased in the EMR group. The histopathological examination of the pancreases indicated slight degenerative changes in some pancreatic endocrine and exocrine cells and slight inflammatory cell infiltrations in the EMR group. At the immunohistochemical examination, marked increase was observed in calcitonin gene related protein and Prostaglandin E2 expressions in pancreatic cells in this group. There were no changes in interleukin-6 expirations. GA ameliorated biochemical and pathological findings in the EMR+GA group. These findings clearly demonstrate that EMR can cause degenerative changes in both endocrine and exocrine pancreas cells in rats during the developmental period and GA has an ameliorative effect. (C) 2017 The Egyptian Society of Radiation Sciences and Applications. Production and hosting by Elsevier B.V.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofJOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCESen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElectromagnetic radiation (EMR); Wi-Fi; Gallic acid; Pancreas; Pathologyen_US
dc.titleThe ameliorative effect of gallic acid on pancreas lesions induced by 2.45 GHz electromagnetic radiation (Wi-Fi) in young ratsen_US
dc.typeArticleen_US
dc.identifier.volume10en_US
dc.identifier.issue3en_US
dc.identifier.startpage233
dc.identifier.startpage233en_US
dc.identifier.endpage240en_US
dc.authorid0000-0003-4575-5653-
dc.identifier.doi10.1016/j.jrras.2017.04.009-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.wosWOS:000410518900010en_US
dc.ownerPamukkale University-
item.languageiso639-1en-
item.fulltextWith Fulltext-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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