Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/23832
Title: Coronary Artery Aneurysms: A Review of the Epidemiology,
Pathophysiology, Diagnosis, and Treatment
Authors: Abou Sherif, S
Tok, OO
Taskoylu, O
Goktekin, O
Kılıç, İsmail Doğu
Keywords: coronary artery aneursym; atherosclerosis; coronary artery disease;
coronary stent; coronary artery ectasia; coronary aneurysm
Publisher: FRONTIERS MEDIA SA
Abstract: Coronary artery aneurysms (CAAs) are uncommon and describe a localized dilatation of a coronary artery segment more than 1.5-fold compared with adjacent normal segments. The incidence of CAAs varies from 0.3 to 5.3%. Ever since the dawn of the interventional era, CAAs have been increasingly diagnosed on coronary angiography. Causative factors include atherosclerosis, Takayasu arteritis, congenital disorders, Kawasaki disease (KD), and percutaneous coronary intervention. The natural history of CAAs remains unclear; however, several recent studies have postulated the underlying molecular mechanisms of CAAs, and genome-wide association studies have revealed several genetic predispositions to CAA. Controversies persist regarding the management of CAAs, and emerging findings support the importance of an early diagnosis in patients predisposed to CAAs, such as in children with KD. This review aims to summarize the present knowledge of CAAs and collate the recent advances regarding the epidemiology, etiology, pathophysiology, diagnosis, and treatment of this disease.
URI: https://hdl.handle.net/11499/23832
https://doi.org/10.3389/fcvm.2017.00024
ISSN: 2297-055X
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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