Evaluation of cornea and anterior chamber results of patients with obstructive sleep apnea syndrome

Abstract

Objective: To evaluate the anterior segment findings measured via corneal topography of patients with obstructive sleep apnea syndrome (OSAS) and to compare the findings with normal subjects.

Methods: A total of 43 eyes from 43 patients with OSAS and 43 eyes from 43 healthy persons who were referred to eye clinics from 2012 to 2016 were randomly selected and included in this retrospective study. Routine eye examination and anterior segment findings measured via corneal topography were recorded for both groups. Central corneal thickness (CCT), keratometry values (K1, K2, and Kmax), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) of the two groups were compared.

Results: The mean CCT values of the control and OSAS groups were 567.23 +/- 31.17 and 544.4 +/- 36.44 (p=0.002), respectively. The mean CV (HR) was found to be 60.51 +/- 8.44 in the control group and 59.78 +/- 3.47 in the OSAS group (p=0.04). There was no statistically significant difference between the OSAS and control groups in terms of mean age, K1, K2, Kmax, ACV, ACD, and ACA (p>0.05). The mean apnea/hypopnea index (AHI) score of the OSAS group was found to be 21.82 +/- 12.79. There was no negative or positive correlation between the AHI score and age, CCT, K1, K2, Km, SCL, SCL, SCA, and CV.

Conclusion: Central corneal thickness and CV are lower in OSAS patients than in normal people.