Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/24494
Title: Mycophenolate mofetil induced remission in steroid-refractory autoimmune hemolytic anemia
Other Titles: Mikofenolat mofetil ile remisyon sağlanan steroide dirençli otoimmün hemolitik anemi
Authors: Özdemir, Emine
Balcı, Yasemin Işık
Evrengül, Havva
Sönmez, Gülay
Bozkurt, Tuğçe
Karadağlı, Eda
Polat, Aziz
Keywords: Steroid; autoimmune hemolytic anemia; mycophenolate mofetil
Publisher: GALENOS YAYINCILIK
Abstract: Autoimmune hemolytic anemia (AIHA) is a disease that is seen in 1/10.000 people and characterized by forming antibodies against red blood cells and degradation of these red blood cells in reticuloendothelial system. Even autoimmune diseases can accompany, it is seen usually idiopathic. Paleness due to anemia, jaundice, tachycardia, darkening in urine color, hepatosplenomegaly are frequently seen clinical findings. Clinically normochrome and normocytic anemia, reticulocytosis, polychromasia in peripheral smear, spherocytes, indirect hyperbilirubinemia and increased lactate dehydrogenase are seen. Direct coombs test is the diagnostic test. Steroids are the first line drugs in treatment. The dosage and the treatment duration is formed according to patient's clinical situation. The treatment is checked by complete blood count, reticulocyte and Coombs test. Immunosuppressor treatments are given to patients that don't respond to treatment in 4-6 weeks or less patients who has recurrence at the time of decreasing the treatment dosage of corticosteroids. In few patient, that did not respond steroids, immunosuppressive treatments are used. Here, we present a patient, who is diagnosed with AIHA that we couldn't manage remission by steroid treatment, and no response to rituxumab as an immunosuppressor, but treated successfully with microphenolat mofetil.
URI: https://hdl.handle.net/11499/24494
https://doi.org/10.4274/meandros.1933
ISSN: 2149-9063
Appears in Collections:Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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