Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30045
Title: Simultaneus estimation and control of glucose-insulin dynamics in type-1 diabetes
Authors: Çetin, Meriç
Beyhan, S.
Keywords: Cubature Kalman filter
Model predictive control
Type-1 diabetes
Biomedical engineering
Blood
Controllers
Dynamics
Insulin
Kalman filters
Predictive control systems
Blood glucose level
Cubature kalman filters
Glucose measurements
Insulin dynamics
Nonlinear model predictive control
Numerical computations
Observer controllers
Portable device
Glucose
Publisher: Institute of Electrical and Electronics Engineers Inc.
Abstract: This paper proposes an observer-controller configuration for the well-known Hovarka Glucose-Insulin dynamics. The aim is to control the blood glucose level without measuring the states in the Hovarka model. In order that nonlinear model predictive control is designed to control the blood glucose level by considering the random inertial glucose inputs under external insulin inputs. For the estimation, a Cubature Kalman filter is designed to estimate the states. Numerical computations are conducted under random glucose inputs from the meals where the applied observer-controller configuration provides blood glucose control without measuring the states. As a result, by using a single subcutaneous glucose measurement, the Hovarka glucose-insuling dynamics can be controlled for a possible portable device in future. © 2019 IEEE.
URI: https://hdl.handle.net/11499/30045
https://doi.org/10.1109/TIPTEKNO.2019.8894958
ISBN: 9781728124209
Appears in Collections:Mühendislik Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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