Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30117
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dc.contributor.authorDogru, A.-
dc.contributor.authorBalkarli, A.-
dc.contributor.authorKaratay, Cemile Canan-
dc.contributor.authorÇobankara, Veli-
dc.contributor.authorSahin, M.-
dc.date.accessioned2020-06-08T12:11:17Z
dc.date.available2020-06-08T12:11:17Z
dc.date.issued2019-
dc.identifier.issn1784-3286-
dc.identifier.urihttps://hdl.handle.net/11499/30117-
dc.identifier.urihttps://doi.org/10.1080/17843286.2018.1495389-
dc.description.abstractObjective: The objective of the study is to evaluate the relation of gout with osteoporosis and serum osteocalcin (OC) levels. Material and methods: Seventy-five patients diagnosed with gout and 55 controls were included in the study. Comorbid conditions and drugs associated with osteoporosis were excluded. The T and Z scores from lumbar spine (L2–L4) and femur (neck, ward, trochanter, total) were determined by dual-energy X-ray absorptiometry (DXA). OC levels were measured by enzyme-linked immunosorbent assay. Results: Osteoporosis according to T scores of lumbar vertebrae L2–L4 was found to be significantly higher in patients with gout compared to the control group (p = 0.02). Lumbar spine T-score was -1.6 in gout group and -1.0 in controls. OC level was 7.9 ng/mL in the gout group and 18.9 ng/mL in the control group. There was a significant difference (p < 0.001). In addition, mean OC level was 12.4 ± 6.9 ng/mL in the patients diagnosed with osteoporosis and 17.2 ± 10.6 ng/mL in the patients that were classified as normal and a significant difference was established between the two groups (p = 0.03). A significant negative correlation was found between OC level and body mass index, age, and age at first attack. Similarly, femoral T-score established a negative correlation with parathyroid hormone, age, age at first attack, and allopurinol dose. Conclusion: Serum OC level can be a useful marker in the assessment of bone turnover and clinicians should keep osteoporosis in mind in gout patients. © 2018, © 2018 Acta Clinica Belgica.en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGouten_US
dc.subjectOsteocalcinen_US
dc.subjectOsteoporosisen_US
dc.subjectalanine aminotransferaseen_US
dc.subjectalkaline phosphataseen_US
dc.subjectallopurinolen_US
dc.subjectC reactive proteinen_US
dc.subjectcreatinineen_US
dc.subjectlow density lipoprotein cholesterolen_US
dc.subjectmonoclonal antibodyen_US
dc.subjectosteocalcinen_US
dc.subjectparathyroid hormoneen_US
dc.subjecttriacylglycerolen_US
dc.subjecturic aciden_US
dc.subjectvitamin Den_US
dc.subjectantigout agenten_US
dc.subjectadulten_US
dc.subjectArticleen_US
dc.subjectblood levelen_US
dc.subjectbody massen_US
dc.subjectbone densityen_US
dc.subjectbone turnoveren_US
dc.subjectcontrolled studyen_US
dc.subjectdual energy X ray absorptiometryen_US
dc.subjectenzyme linked immunosorbent assayen_US
dc.subjectfemaleen_US
dc.subjectfemoralen_US
dc.subjectfemoral necken_US
dc.subjectfemoral t scoreen_US
dc.subjectgouten_US
dc.subjecthumanen_US
dc.subjectlumbar spineen_US
dc.subjectlumbar t scoreen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectmiddle ageden_US
dc.subjectosteopeniaen_US
dc.subjectosteoporosisen_US
dc.subjectscoring systemen_US
dc.subjectageen_US
dc.subjectblooden_US
dc.subjectbone remodelingen_US
dc.subjectdiagnostic imagingen_US
dc.subjectfemuren_US
dc.subjectlumbar vertebraen_US
dc.subjectphoton absorptiometryen_US
dc.subjectproceduresen_US
dc.subjectturkey (bird)en_US
dc.subjectAbsorptiometry, Photonen_US
dc.subjectAge Factorsen_US
dc.subjectAllopurinolen_US
dc.subjectBody Mass Indexen_US
dc.subjectBone Remodelingen_US
dc.subjectCorrelation of Dataen_US
dc.subjectFemaleen_US
dc.subjectFemuren_US
dc.subjectGout Suppressantsen_US
dc.subjectHumansen_US
dc.subjectLumbar Vertebraeen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectTurkeyen_US
dc.titleBone mineral density and serum osteocalcin levels in patients with gouten_US
dc.typeArticleen_US
dc.identifier.volume74en_US
dc.identifier.issue4en_US
dc.identifier.startpage252
dc.identifier.startpage252en_US
dc.identifier.endpage257en_US
dc.identifier.doi10.1080/17843286.2018.1495389-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid30004299en_US
dc.identifier.scopus2-s2.0-85049894465en_US
dc.identifier.wosWOS:000472109700005en_US
dc.identifier.scopusqualityQ3-
dc.ownerPamukkale University-
item.languageiso639-1en-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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