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https://hdl.handle.net/11499/30117
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dogru, A. | - |
dc.contributor.author | Balkarli, A. | - |
dc.contributor.author | Karatay, Cemile Canan | - |
dc.contributor.author | Çobankara, Veli | - |
dc.contributor.author | Sahin, M. | - |
dc.date.accessioned | 2020-06-08T12:11:17Z | |
dc.date.available | 2020-06-08T12:11:17Z | |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1784-3286 | - |
dc.identifier.uri | https://hdl.handle.net/11499/30117 | - |
dc.identifier.uri | https://doi.org/10.1080/17843286.2018.1495389 | - |
dc.description.abstract | Objective: The objective of the study is to evaluate the relation of gout with osteoporosis and serum osteocalcin (OC) levels. Material and methods: Seventy-five patients diagnosed with gout and 55 controls were included in the study. Comorbid conditions and drugs associated with osteoporosis were excluded. The T and Z scores from lumbar spine (L2–L4) and femur (neck, ward, trochanter, total) were determined by dual-energy X-ray absorptiometry (DXA). OC levels were measured by enzyme-linked immunosorbent assay. Results: Osteoporosis according to T scores of lumbar vertebrae L2–L4 was found to be significantly higher in patients with gout compared to the control group (p = 0.02). Lumbar spine T-score was -1.6 in gout group and -1.0 in controls. OC level was 7.9 ng/mL in the gout group and 18.9 ng/mL in the control group. There was a significant difference (p < 0.001). In addition, mean OC level was 12.4 ± 6.9 ng/mL in the patients diagnosed with osteoporosis and 17.2 ± 10.6 ng/mL in the patients that were classified as normal and a significant difference was established between the two groups (p = 0.03). A significant negative correlation was found between OC level and body mass index, age, and age at first attack. Similarly, femoral T-score established a negative correlation with parathyroid hormone, age, age at first attack, and allopurinol dose. Conclusion: Serum OC level can be a useful marker in the assessment of bone turnover and clinicians should keep osteoporosis in mind in gout patients. © 2018, © 2018 Acta Clinica Belgica. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Taylor and Francis Ltd. | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Gout | en_US |
dc.subject | Osteocalcin | en_US |
dc.subject | Osteoporosis | en_US |
dc.subject | alanine aminotransferase | en_US |
dc.subject | alkaline phosphatase | en_US |
dc.subject | allopurinol | en_US |
dc.subject | C reactive protein | en_US |
dc.subject | creatinine | en_US |
dc.subject | low density lipoprotein cholesterol | en_US |
dc.subject | monoclonal antibody | en_US |
dc.subject | osteocalcin | en_US |
dc.subject | parathyroid hormone | en_US |
dc.subject | triacylglycerol | en_US |
dc.subject | uric acid | en_US |
dc.subject | vitamin D | en_US |
dc.subject | antigout agent | en_US |
dc.subject | adult | en_US |
dc.subject | Article | en_US |
dc.subject | blood level | en_US |
dc.subject | body mass | en_US |
dc.subject | bone density | en_US |
dc.subject | bone turnover | en_US |
dc.subject | controlled study | en_US |
dc.subject | dual energy X ray absorptiometry | en_US |
dc.subject | enzyme linked immunosorbent assay | en_US |
dc.subject | female | en_US |
dc.subject | femoral | en_US |
dc.subject | femoral neck | en_US |
dc.subject | femoral t score | en_US |
dc.subject | gout | en_US |
dc.subject | human | en_US |
dc.subject | lumbar spine | en_US |
dc.subject | lumbar t score | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | middle aged | en_US |
dc.subject | osteopenia | en_US |
dc.subject | osteoporosis | en_US |
dc.subject | scoring system | en_US |
dc.subject | age | en_US |
dc.subject | blood | en_US |
dc.subject | bone remodeling | en_US |
dc.subject | diagnostic imaging | en_US |
dc.subject | femur | en_US |
dc.subject | lumbar vertebra | en_US |
dc.subject | photon absorptiometry | en_US |
dc.subject | procedures | en_US |
dc.subject | turkey (bird) | en_US |
dc.subject | Absorptiometry, Photon | en_US |
dc.subject | Age Factors | en_US |
dc.subject | Allopurinol | en_US |
dc.subject | Body Mass Index | en_US |
dc.subject | Bone Remodeling | en_US |
dc.subject | Correlation of Data | en_US |
dc.subject | Female | en_US |
dc.subject | Femur | en_US |
dc.subject | Gout Suppressants | en_US |
dc.subject | Humans | en_US |
dc.subject | Lumbar Vertebrae | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Turkey | en_US |
dc.title | Bone mineral density and serum osteocalcin levels in patients with gout | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 74 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 252 | |
dc.identifier.startpage | 252 | en_US |
dc.identifier.endpage | 257 | en_US |
dc.identifier.doi | 10.1080/17843286.2018.1495389 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 30004299 | en_US |
dc.identifier.scopus | 2-s2.0-85049894465 | en_US |
dc.identifier.wos | WOS:000472109700005 | en_US |
dc.identifier.scopusquality | Q3 | - |
dc.owner | Pamukkale University | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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