Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30157
Title: Relationship of apathy with depressive symptom severity and cognitive functions in geriatric depression
Authors: Sözeri-Varma, Gülfizar
Bingöl, C.
Topak, Osman Zulkif
Enli, Yaşar
Özdel, Osman İsmail
Keywords: Apathy
Cognitive function
Depression
Geriatric depression
adult
aged
apathy
Apathy Evaluation Scale
Article
cognition
cognitive defect
controlled study
disease association
disease severity
executive function
family life
female
follow up
geriatric patient
Hamilton Anxiety Scale
Hamilton Depression Rating Scale
human
late life depression
leisure
major clinical study
major depression
male
middle aged
Mini Mental State Examination
Montgomery Asberg Depression Rating Scale
Montreal cognitive assessment
neuropsychological test
scoring system
Sheehan Disability Scale
social life
Structured Clinical Interview for DSM Disorders
very elderly
visual spatial executive function
Publisher: Turkish Neuropsychiatric Society
Abstract: Introduction: Apathy which is known as loss of primary motivation is observed more frequently in elderly depression in comparison with younger adults. It is put forth that apathy is related with depressive symptom severity and cognitive functions, that the existence of apathy may be a predictor of neurocognitive impairment. The objective of this study was to examine the apathy levels in elderly patients with major depression as well as the relationship between depressive symptom severity and cognitive functions. Methods: The study was carried out with 40 major depressive disorder patients (MDD) aged 60 and above, 40 healthy controls aged 60 and above. Sociodemographic data form, structured psychiatric interview (SCID-I), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Montgomery-Asberg Depression Rating Scale (MADRS), Standardized Mini Mental State Examination (SMMSE), Montreal Cognitive Assessment Scale (MoCA), Apathy Evaluation Scale (AES) and Sheehan Disability Scale (SDS) were applied to the participants. Results: In our study, HAM-D, HAM-A and MADRS scale scores of MDD group was determined to be higher in comparison with those of the healthy control group. A positive correlation was determined in the MDD groups between the AES scores and depressive symptom severity, whereas a negative correlation was determined between the AES scores and cognitive functions. The SMMSE and MoCA scores of the geriatric MDD group were determined to be lower in comparison with healthy control group. Low performance was observed in the geriatric MDD group especially in the fields of orientation, visual/spatial functions, memory and language. Functionality was found to be lower in MDB group than in the control group, and functionality decreased as the level of apathy increased. Conclusion: Our results indicate that the apathy levels in geriatric depression are higher in comparison with the control group. Cognitive functions are affected adversely in geriatric patients in major depressive disorder, depressive symptom severity, impairment in cognitive functions and functionality are observed to be related with apathy level. © 2018 by Turkish Association of Neuropsychiatry.
URI: https://hdl.handle.net/11499/30157
https://doi.org/10.29399/npa.22931
ISSN: 1300-0667
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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