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https://hdl.handle.net/11499/30194
Title: | Heterostructures of mesoporous TiO 2 and SnO 2 nanocatalyst for improved electrochemical oxidation ability of vitamin B6 in pharmaceutical tablets | Authors: | Manoj, D. Rajendran, S. Qin, J. Sundaravadivel, E. Yola, M.L. Atar, Necip Gracia, F. |
Keywords: | Electrochemical sensor Mesoporous Tin oxide (SnO 2 ) cocatalyst Titanium dioxide (TiO 2 ) Vitamin B6 Biosynthesis Coenzymes Electrochemical oxidation Electrochemical sensors Glass membrane electrodes Mesoporous materials Nanocatalysts Tin dioxide Tin oxides TiO2 nanoparticles Titanium dioxide Titanium oxides Voltammetry Cocatalyst Differential pulse voltammetry Electrochemical platforms Electrochemical surface area Pharmaceutical quality control Titanium dioxides (TiO2) Vitamin B-6 Chemical detection nanocomposite nanoparticle pyridoxine tin oxide nanoparticle titanium dioxide nanoparticle unclassified drug stannic oxide tin derivative titanium titanium dioxide Article chemical structure cyclic potentiometry differential pulse voltammetry electrochemical analysis high resolution transmission electron microscopy impedance spectroscopy limit of detection nanocatalyst nanofabrication oxidation priority journal reproducibility sensitivity analysis surface area surface property tablet X ray diffraction X ray fluorescence X ray photoemission spectroscopy catalysis chemistry electrode oxidation reduction reaction porosity sensitivity and specificity Catalysis Electrochemical Techniques Electrodes Limit of Detection Nanocomposites Oxidation-Reduction Porosity Sensitivity and Specificity Tablets Tin Compounds Titanium Vitamin B 6 |
Publisher: | Academic Press Inc. | Abstract: | The detection of water soluble vitamins using electrochemical method is widely established in pharmaceutical quality control laboratories, and especially the recent advances in hybrid heterostrucure nanomaterials has devoted to enhance the significant analytical parameters like sensitivity, selectivity and fast response time. Herein, we report the synthesis of a hybrid heterostructure comprising SnO 2 nanoparticles supported mesoporous TiO 2 , and the obtained nanocomposite were fabricated over glassy carbon electrode (GCE) for the electrochemical oxidation of vitamin B 6 in pharmaceutical tablets. The designed SnO 2 -TiO 2 /GC modified electrode exhibits well-defined oxidation peak with lowering over-potential and larger signal response compared to the pristine counterparts, and it is mainly due to the formation of abundant active surface layer offered by SnO 2 cocatalyst, and thus significantly enhances the electrochemical surface area. Differential pulse voltammetry (DPV) measurements revealed a sharp increase in the anodic peak current upon addition of increasing concentration of vitamin B 6 . The analytical performance of the modified electrode displayed a wide linear range (0.1–31.4 µM), high selectivity, and excellent sensitivity (759.73 µA mM -1 cm -2 ) with low detection limit (35 nM). Thus, the resultant mesoporous hybrid nanocatalyst provides an efficient electrochemical platform for determination of various potential analytes. © 2019 Elsevier Inc. | URI: | https://hdl.handle.net/11499/30194 https://doi.org/10.1016/j.jcis.2019.01.118 |
ISSN: | 0021-9797 |
Appears in Collections: | Mühendislik Fakültesi Koleksiyonu PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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