Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30207
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dc.contributor.authorKirişci, Ö.-
dc.contributor.authorÇalışkan, Ahmet-
dc.date.accessioned2020-06-08T12:11:45Z
dc.date.available2020-06-08T12:11:45Z
dc.date.issued2019-
dc.identifier.issn2008-3645-
dc.identifier.urihttps://hdl.handle.net/11499/30207-
dc.identifier.urihttps://doi.org/10.5812/jjm.80872-
dc.description.abstractBackground: The genotype determination is of importance in the clinical management of hepatitis C virus (HCV) infection. Objectives: The aim of this study was to evaluate the distribution of genotypes in HCV patients in the Kahramanmaras region, Turkey, and determine if the genotype rates of Syrian refugee patients with hepatitis C are different from the population they migrated to. Methods: Blood samples sent to the microbiology laboratory between September 2014andFebruary 2018 were examined with genotyping using a real-time PCR reagent kit. Results: The results of 274 patients who were HCV genotype-assigned were obtained from the hospital electronic information system. Of 230 Turkish HCV patients, 121 (52.8%) were identified as genotype 3, 100 (43.3%) as genotype 1, five (2.2%) as genotype 2, and four (1.7%) as genotype 4. Of the 44 Syrian refugee patients, 24 (54.5%) were identified as genotype 1, 18 (40.9%) as genotype 4, one (2.3%) as genotype 2, and one (2.3%) as genotype 3. Conclusions: Predominant genotype 3 with the prevalence of 52.8% was seen to be more frequent in the current study region than in other regions of Turkey, demonstrating the highest rate of genotype 3 infection in Turkey to date. In Syria, the predominant HCV genotype is genotype 4 with a 57% prevalence, followed by genotype 1 with 29%. In the Syrian refugees, however, the current study showed genotype 1 was more frequent than genotype 4 (54.5% vs. 40.9%). This suggests that HCV genotypes may be affected by situations such as war and migration. © 2019 Author(s). All rights reserved.en_US
dc.language.isoenen_US
dc.publisherKowsar Medical Publishing Companyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenotypeen_US
dc.subjectHepatitis C Virusen_US
dc.subjectRefugeesen_US
dc.subjectTurkeyen_US
dc.subjectvirus RNAen_US
dc.subjectadulten_US
dc.subjectArticleen_US
dc.subjectDNA extractionen_US
dc.subjectfemaleen_US
dc.subjectgenetic analysisen_US
dc.subjectgenotypeen_US
dc.subjecthepatitis Cen_US
dc.subjectHepatitis C virusen_US
dc.subjectHepatitis C virus genotype 1en_US
dc.subjectHepatitis C virus genotype 3en_US
dc.subjecthumanen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectmigrationen_US
dc.subjectpopulation migrationen_US
dc.subjectprevalenceen_US
dc.subjectreal time polymerase chain reactionen_US
dc.subjectrefugeeen_US
dc.subjectSyrianen_US
dc.subjectvirus identificationen_US
dc.titleThe predominance of genotype 3 in Hepatitis C virus in the province of kahramanmaras, Turkey/Genotype distribution of syrian refugee patients with Hepatitis C in Kahramanmaras Provinceen_US
dc.typeArticleen_US
dc.identifier.volume12en_US
dc.identifier.issue4en_US
dc.authorid0000-0002-1156-3787-
dc.identifier.doi10.5812/jjm.80872-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-85070191784en_US
dc.identifier.wosWOS:000466873400004en_US
dc.identifier.scopusqualityQ3-
dc.ownerPamukkale University-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.openairetypeArticle-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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