Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/30208
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Becerir, T. | - |
dc.contributor.author | Yüksel, Selçuk | - |
dc.contributor.author | Evrengül, Havva | - |
dc.contributor.author | Ergin, Ahmet | - |
dc.contributor.author | Enli, Yaşar | - |
dc.date.accessioned | 2020-06-08T12:11:46Z | |
dc.date.available | 2020-06-08T12:11:46Z | |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0301-1623 | - |
dc.identifier.uri | https://hdl.handle.net/11499/30208 | - |
dc.identifier.uri | https://doi.org/10.1007/s11255-019-02102-8 | - |
dc.description.abstract | Purpose: Acute pyelonephritis is associated with considerable morbidity and potential for renal scarring. Pentraxin3 (PTX3) is a recently discovered mediator of inflammation. The objective of this study was to investigate the changes in serum and urine PTX3 levels in children who had a history of pyelonephritis and were diagnosed with renal parenchymal scar (RPS) and/or vesicoureteral reflux (VUR). Methods: The study included 88 children (31 males, 57 females) aged between 3 months and 18 years. The children included in the study were divided into four groups: VUR with RPS (Group 1), RPS without VUR (Group 2), VUR without RPS (Group 3), and healthy children without a history of hydronephrosis or UTI history (Group 4). After the initial evaluation, the participants were further divided into two more groups and re-evaluated: Children with RPS (Group 1 + 2), children without RPS (Group 3 + 4), children with VUR (Group 1 + 3), and children without VUR (Group 2 + 4). Results: We found that urine pentraxin 3 (uPTX3) and uPTX3/Creatinine levels were significantly higher in the groups with renal scar with or without VUR than the ones without RPS [mean uPTX3, 3.5 pg/ml (min–max 0.0022–12.3668) vs. 2.2 pg/ml (min–max 0.0022–18.5868) and uPTX3/creatinine, 10.5 pg/mg (min–max 0.0035–51.1) vs. 5.8 pg/mg (min–max 0.0004–78.7), p < 0.01]. uPTX3 levels were not different among the groups with and without VUR. In addition, serum PTX3 levels were not different among the groups. Conclusions: We showed that urinary PTX3 increased only in patients with scarred kidneys. These results might be helpful to predict RPS due to past pyelonephritis. © 2019, Springer Nature B.V. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Netherlands | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Children | en_US |
dc.subject | Pentraxin 3 | en_US |
dc.subject | Renal scar | en_US |
dc.subject | Vesicoureteral reflux | en_US |
dc.subject | creatinine | en_US |
dc.subject | pentraxin 3 | en_US |
dc.subject | biological marker | en_US |
dc.subject | C reactive protein | en_US |
dc.subject | serum amyloid P | en_US |
dc.subject | acute pyelonephritis | en_US |
dc.subject | adolescent | en_US |
dc.subject | adult | en_US |
dc.subject | Article | en_US |
dc.subject | child | en_US |
dc.subject | clinical evaluation | en_US |
dc.subject | correlational study | en_US |
dc.subject | disease association | en_US |
dc.subject | female | en_US |
dc.subject | human | en_US |
dc.subject | infant | en_US |
dc.subject | kidney parenchyma | en_US |
dc.subject | kidney scar | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | medical history | en_US |
dc.subject | protein urine level | en_US |
dc.subject | urinary excretion | en_US |
dc.subject | vesicoureteral reflux | en_US |
dc.subject | acute disease | en_US |
dc.subject | blood | en_US |
dc.subject | case control study | en_US |
dc.subject | complication | en_US |
dc.subject | metabolism | en_US |
dc.subject | preschool child | en_US |
dc.subject | pyelonephritis | en_US |
dc.subject | scar | en_US |
dc.subject | urine | en_US |
dc.subject | Acute Disease | en_US |
dc.subject | Adolescent | en_US |
dc.subject | Biomarkers | en_US |
dc.subject | C-Reactive Protein | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | Child | en_US |
dc.subject | Child, Preschool | en_US |
dc.subject | Cicatrix | en_US |
dc.subject | Creatinine | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Infant | en_US |
dc.subject | Male | en_US |
dc.subject | Pyelonephritis | en_US |
dc.subject | Serum Amyloid P-Component | en_US |
dc.subject | Vesico-Ureteral Reflux | en_US |
dc.title | Urinary excretion of pentraxin-3 correlates with the presence of renal scar following acute pyelonephritis in children | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 51 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 571 | |
dc.identifier.startpage | 571 | en_US |
dc.identifier.endpage | 577 | en_US |
dc.authorid | 0000-0001-9415-1640 | - |
dc.identifier.doi | 10.1007/s11255-019-02102-8 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 30796728 | en_US |
dc.identifier.scopus | 2-s2.0-85061988993 | en_US |
dc.identifier.wos | WOS:000464869600002 | en_US |
dc.identifier.scopusquality | Q2 | - |
dc.owner | Pamukkale University | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
CORE Recommender
SCOPUSTM
Citations
13
checked on Jan 4, 2025
WEB OF SCIENCETM
Citations
5
checked on Apr 1, 2025
Page view(s)
64
checked on Feb 8, 2025
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.