Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30467
Title: A new promising treatment strategy for carbon monoxide poisoning: High flow nasal cannula oxygen therapy
Authors: Tomruk, O.
Karaman, K.
Erdur, Bülent
Armagan, H.H.
Beceren, N.G.
Oskay, A.
Bircan, H.A.
Keywords: Anoxia
Carbon monoxide poisoning
Emergency service
Hospital
carboxyhemoglobin
oxygen
adult
arterial gas
arterial oxygen tension
Article
blood gas analysis
carbon monoxide intoxication
controlled study
female
human
hyperbaric oxygen therapy
hypoxemia
major clinical study
male
oxygen tension
retrospective study
blood
cannula
hospital emergency service
hypoxia
middle aged
noninvasive ventilation
oxygen therapy
procedures
respiratory failure
treatment outcome
Adult
Blood Gas Analysis
Cannula
Carbon Monoxide Poisoning
Carboxyhemoglobin
Emergency Service, Hospital
Female
Humans
Hypoxia
Male
Middle Aged
Noninvasive Ventilation
Oxygen
Oxygen Inhalation Therapy
Respiratory Insufficiency
Retrospective Studies
Treatment Outcome
Publisher: International Scientific Information, Inc.
Abstract: Background: High-flow nasal cannula (HFNC) is an alternative to conventional normobaric oxygen therapy (NBO) for hypoxemic patients. Since nothing is known about its effect on carbon monoxide (CO) poisoning, we hypothesized that HFNC might be a useful device in the treatment of CO poisoning victims. Material/Methods: We retrospectively reviewed the medical records of patients who were admitted consecutively to the emergency department with CO intoxication. Patients were divided into 2 groups: patients treated with HFNC and patients treated with conventional face mask (CFM). Demographic data, pretreatment, and control (after 1 hour) arterial blood gas analyses values of the patients were evaluated. Results: Sixty-eight patients (mean age 35.8±18.7 years) were included in this study. NBO was given via HFNC to 38 patients (55.9%), and via CFM to 30 patients (44.1%). The demographic characteristics and pretreatment values of carboxy-hemoglobin (COHb) were similar in the 2 groups. The mean COHb value of the HFNC group at the first hour was found significantly lower than the CFM group: 9.5±4.7 and 12.0±5.1, respectively (P=0.041). Improvement of COHb level was significantly higher in the HFNC group compared to the CFM group: 12.5±4.5 versus 6.7±3.7, respectively (P=0.001). Conclusions: HFNC was superior than CFM in alleviating COHb levels in the victims of CO poisoning. We believe that using HFNC will increase patient comfort by shortening the duration of treatment in emergency department settings, especially in patients who have mild clinical findings of CO poisoning. © Med Sci Monit, 2019.
URI: https://hdl.handle.net/11499/30467
https://doi.org/10.12659/MSM.914800
ISSN: 1234-1010
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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