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https://hdl.handle.net/11499/30501
Title: | Diagnostic performance of contrast-enhanced and unenhanced combined pulmonary artery MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism | Authors: | Kaya, F. Ufuk, Furkan. Karabulut, N. |
Keywords: | gadobutrol iopromide contrast medium adult aged Article clinical article computed tomographic angiography contrast enhancement deep vein thrombosis diagnostic accuracy Doppler ultrasonography female femoral vein heart left atrium human iliac vein image quality inferior cava vein lower limb lung angiography lung embolism magnetic resonance venography male nuclear magnetic resonance imaging patient pleura effusion popliteal vein predictive value prospective study pulmonary artery sensitivity and specificity thorax pain three dimensional imaging venous thromboembolism diagnostic imaging magnetic resonance angiography middle aged procedures vascularization vein thrombosis very elderly young adult Adult Aged Aged, 80 and over Computed Tomography Angiography Contrast Media Female Humans Lower Extremity Magnetic Resonance Angiography Male Middle Aged Prospective Studies Pulmonary Artery Pulmonary Embolism Sensitivity and Specificity Ultrasonography, Doppler Venous Thromboembolism Venous Thrombosis Young Adult |
Publisher: | British Institute of Radiology | Abstract: | Objective: We aimed to determine the diagnostic performance of the contrast-enhanced and unenhanced combined pulmonary arterial MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism (VTE). Methods: 44 patients who underwent CT pulmonary angiography (CTPA) for suspected PE constituted the study population. Patients underwent combined pulmonary and lower extremity MRI, and Doppler ultrasonography within 72 h after CTPA. Combined MRI included two sequences: unenhanced steady-state free precession (SSFP) and contrast-enhanced three-dimensional (3D) gradient echo (GRE). The presence of emboli in pulmonary arteries and thrombi in lower extremity veins on 3D-GRE and SSFP sequences was recorded. results: CTPA showed a total of 244 emboli in 33 (75%) patients whereas contrast-enhanced 3D-GRE MRI showed deep vein thrombosis (DVT) in 34 (77%) subjects. Sensitivities for SSFP vs 3D-GRE MRI respectively in PE detection were 87.9 vs 100% on a per-patient basis, and 53.7 vs 73% on a per-embolus basis. Of 34 patients with established DVT, 31 (91%) were detected by Doppler ultrasound and 29 (85%) were detected by SSFP technique respectively. Conclusion: Both contrast-enhanced and unenhanced combined MRI of acute PE and DVT are feasible one-stop-shopping techniques in patients with suspected thromboembolism. Advances in knowledge: Pulmonary VTE is a common disease with high mortality. Non-invasive techniques withhigh accuracy are required for the assessment of VTE. CT-related radiation and contrast material risks cause concerns. MRI is a radiation-free technique evaluating the vessels with and without contrast. Combined contrast enhancedor unenhanced pulmonary and lower extremity MRI is feasible in patients with suspected thromboembolism. © 2019 The Authors. Published by the British Institute of Radiology | URI: | https://hdl.handle.net/11499/30501 https://doi.org/10.1259/bjr.20180695 |
ISSN: | 0007-1285 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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