Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/30501
Title: Diagnostic performance of contrast-enhanced and unenhanced combined pulmonary artery MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism
Authors: Kaya, F.
Ufuk, Furkan.
Karabulut, N.
Keywords: gadobutrol
iopromide
contrast medium
adult
aged
Article
clinical article
computed tomographic angiography
contrast enhancement
deep vein thrombosis
diagnostic accuracy
Doppler ultrasonography
female
femoral vein
heart left atrium
human
iliac vein
image quality
inferior cava vein
lower limb
lung angiography
lung embolism
magnetic resonance venography
male
nuclear magnetic resonance imaging
patient
pleura effusion
popliteal vein
predictive value
prospective study
pulmonary artery
sensitivity and specificity
thorax pain
three dimensional imaging
venous thromboembolism
diagnostic imaging
magnetic resonance angiography
middle aged
procedures
vascularization
vein thrombosis
very elderly
young adult
Adult
Aged
Aged, 80 and over
Computed Tomography Angiography
Contrast Media
Female
Humans
Lower Extremity
Magnetic Resonance Angiography
Male
Middle Aged
Prospective Studies
Pulmonary Artery
Pulmonary Embolism
Sensitivity and Specificity
Ultrasonography, Doppler
Venous Thromboembolism
Venous Thrombosis
Young Adult
Publisher: British Institute of Radiology
Abstract: Objective: We aimed to determine the diagnostic performance of the contrast-enhanced and unenhanced combined pulmonary arterial MRI and magnetic resonance venography techniques in the diagnosis of venous thromboembolism (VTE). Methods: 44 patients who underwent CT pulmonary angiography (CTPA) for suspected PE constituted the study population. Patients underwent combined pulmonary and lower extremity MRI, and Doppler ultrasonography within 72 h after CTPA. Combined MRI included two sequences: unenhanced steady-state free precession (SSFP) and contrast-enhanced three-dimensional (3D) gradient echo (GRE). The presence of emboli in pulmonary arteries and thrombi in lower extremity veins on 3D-GRE and SSFP sequences was recorded. results: CTPA showed a total of 244 emboli in 33 (75%) patients whereas contrast-enhanced 3D-GRE MRI showed deep vein thrombosis (DVT) in 34 (77%) subjects. Sensitivities for SSFP vs 3D-GRE MRI respectively in PE detection were 87.9 vs 100% on a per-patient basis, and 53.7 vs 73% on a per-embolus basis. Of 34 patients with established DVT, 31 (91%) were detected by Doppler ultrasound and 29 (85%) were detected by SSFP technique respectively. Conclusion: Both contrast-enhanced and unenhanced combined MRI of acute PE and DVT are feasible one-stop-shopping techniques in patients with suspected thromboembolism. Advances in knowledge: Pulmonary VTE is a common disease with high mortality. Non-invasive techniques withhigh accuracy are required for the assessment of VTE. CT-related radiation and contrast material risks cause concerns. MRI is a radiation-free technique evaluating the vessels with and without contrast. Combined contrast enhancedor unenhanced pulmonary and lower extremity MRI is feasible in patients with suspected thromboembolism. © 2019 The Authors. Published by the British Institute of Radiology
URI: https://hdl.handle.net/11499/30501
https://doi.org/10.1259/bjr.20180695
ISSN: 0007-1285
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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