Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/32477
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dc.contributor.authorIsikgoz Tasbakan, M-
dc.contributor.authorEren Kutsoylu, O-
dc.contributor.authorPullukcu, H-
dc.contributor.authorSayin Kutlu, S-
dc.contributor.authorOzturk, B-
dc.contributor.authorKaya, O-
dc.contributor.authorTurhan, O-
dc.contributor.authorSenol Akat, Sebnem-
dc.contributor.authorAlp Cavus, Sema-
dc.contributor.authorKutlu, Murat-
dc.contributor.authorMermut, Gulsen-
dc.contributor.authorMetin, Dilek Yesim-
dc.contributor.authorOzhak, Betil-
dc.contributor.authorErgin, Cagri-
dc.contributor.authorCetin, Cigdem Banu-
dc.contributor.authorErtugrul, Mustafa Bulent-
dc.contributor.authorAvkan Oguz, Vildan-
dc.contributor.authorYapar, Nur-
dc.date.accessioned2020-06-08T13:48:31Z-
dc.date.available2020-06-08T13:48:31Z-
dc.date.issued2019-
dc.identifier.urihttps://hdl.handle.net/11499/32477-
dc.identifier.urihttps://doi.org/10.5578/flora.67777-
dc.description.abstractIntroduction: Fungal infections are vital problems worldwide and their incidence have increased along with changing patient profile. Particularly candida species is still the most commonfungal agent, and the significance of non-albicans candida species have gained importance in recent years. In the present study, it was aimed to evaluate retrospectively the risk factors and distribution of candida species in patients with invasive candida infections, who were treated with anidulafungin.en_US
dc.description.abstractMaterials and Methods: In the first three years (1 January 2012 to 31 December 2014) when anidulafungin came out in our country, we retrospectively evaluated the data of the patients with invasive candida infections who were treated by anidulafungin for more than 48 hours in seven university hospitals. Data were recorded to the case report forms.en_US
dc.description.abstractResults: Two hundreds and fifty-seven patients were included into the study. Fifty-six percent of the patients were male and mean age was 58.57 +/- 19.5 years. Two hundreds and three patients (79%) were hospitalized in intensive care units, 37 (14.3%) in internal medicine services, and 17 (0.07%) in surgery services. As previously described, we detected antibiotic usage in the last month (%96.9), presence of urinary catheter (90.3%) and presence of central venous catheter (82.1%) as risk factors for invasive candida infections. More than half of the patients (57.1%) with central venous catheter had candidemia. Sixty-six (47.7%) of the blood isolates were Candida albicans, 33 (23.7%) were Candida parapsilosis, 17 (12.2%) were Candida tropicalis and 13 (9.4%) were Candida glabrata. During follow up, 64.5% of 124 patients whose catheters couldn't be taken off and 47.6% of 86 patients whose catheters could be taken off died. During anidulafungin treatment, one anaphylaxis, one skin eruption and one thrombocytopenia were seen as side effects.en_US
dc.description.abstractConclusion: In our study, we found that removal of central venous catheter of the patients with candidemia was a positive effect on mortality. We suggest that patients with candidemia, insisting on catheter removal besides antifungal treatment is necessary. We observed that anidulafungin is an effective and safe choice in invasive candida infections.en_US
dc.language.isotren_US
dc.publisherBILIMSEL TIP YAYINEVIen_US
dc.relation.ispartofFLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISIen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCandidemia; Anidulafungin; Candida species; Central venous cathetersen_US
dc.titleMulticenter Analysis of Anidulafungin Use in Invasive Candida Infectionsen_US
dc.typeArticleen_US
dc.identifier.volume24en_US
dc.identifier.issue2en_US
dc.identifier.startpage136-
dc.identifier.startpage136en_US
dc.identifier.endpage142en_US
dc.authorid0000-0001-7783-8723-
dc.identifier.doi10.5578/flora.67777-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.trdizinid321380en_US
dc.identifier.wosWOS:000473317400009en_US
dc.ownerPamukkale University-
item.openairetypeArticle-
item.languageiso639-1tr-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.cerifentitytypePublications-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.02. Internal Medicine-
crisitem.author.dept14.03. Basic Medical Sciences-
Appears in Collections:Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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