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https://hdl.handle.net/11499/36926
Title: | The early and late efficacy of single-pass fractional carbondioxide laser, fractional radiofrequency, and their combination in acne scars: A prospective, split-face, single-blinded, controlled clinical study | Authors: | Kaçar, Nida Dursun, R. Akbay, M. Gökşin, Şule |
Keywords: | acne carbondioxide laser combination fractional laser radiofrequency scar therapy treatment 2 phenoxyethanol filler isotretinoin lidocaine steroid sunscreen tetracaine Triticum vulgare extract adult Article atrophic scar bleeding tendency clinical article clinical effectiveness clinical examination connective tissue disease controlled clinical trial controlled study dermatitis disease severity edema erythema face female fractional radiofrequency therapy human hypertrophic scar immunosuppressive treatment keloid lichen planus low level laser therapy male pain patient satisfaction photosensitivity prospective study psoriasis radiofrequency therapy sex difference single blind procedure topical anesthesia visual analog scale vitiligo young adult |
Publisher: | Blackwell Publishing Inc. | Abstract: | We investigated the effectiveness of fractional carbon dioxide laser (FCO2) vs fractional radiofrequency (FRF) and FCO2 vs FRF plus FCO2 combination in the treatment of acne scars. Twenty-seven patients were included. Scar severity was scored with “Echelle d'évaluation clinique des cicatrices d'acné” (ECCA) by a dermatologist blinded to treatment. FCO2 and FRF were administered to the right and left halves of the patients' faces, respectively, at the first three visits, once a month. At the fourth visit, FCO2 was administered to both sides. Last evaluation was performed 6 months after the last treatment. Mean ECCA scores for both face halves decreased gradually at each visit compared with Visit-1; however, the effect size of decrease was higher in the right half of the face and in terms of gender differences was higher in women for both sides that the difference was more pronounced for the FRF side. There was no statistically significant change in the mean VAS patient satisfaction scores in the following visits compared with Visit-2 on both halves (P >.05). Side effects were similar; but lasted longer in the FCO2 side. Both FCO2 and FRF are effective treatment methods in the treatment of atrophic acne scars. Combining FCO2 to FRF improves patient satisfaction. FRF may achieve better results in women compared with men. To our knowledge the study is unique prospective, controlled clinical study comparing the efficacy of FCO2 and FRF plus FCO2 combination treatments. © 2020 Wiley Periodicals LLC. | URI: | https://hdl.handle.net/11499/36926 https://doi.org/10.1111/dth.14444 |
ISSN: | 1396-0296 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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