Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/36926
Title: The early and late efficacy of single-pass fractional carbondioxide laser, fractional radiofrequency, and their combination in acne scars: A prospective, split-face, single-blinded, controlled clinical study
Authors: Kaçar, Nida
Dursun, R.
Akbay, M.
Gökşin, Şule
Keywords: acne
carbondioxide laser
combination
fractional laser
radiofrequency
scar
therapy
treatment
2 phenoxyethanol
filler
isotretinoin
lidocaine
steroid
sunscreen
tetracaine
Triticum vulgare extract
adult
Article
atrophic scar
bleeding tendency
clinical article
clinical effectiveness
clinical examination
connective tissue disease
controlled clinical trial
controlled study
dermatitis
disease severity
edema
erythema
face
female
fractional radiofrequency therapy
human
hypertrophic scar
immunosuppressive treatment
keloid
lichen planus
low level laser therapy
male
pain
patient satisfaction
photosensitivity
prospective study
psoriasis
radiofrequency therapy
sex difference
single blind procedure
topical anesthesia
visual analog scale
vitiligo
young adult
Publisher: Blackwell Publishing Inc.
Abstract: We investigated the effectiveness of fractional carbon dioxide laser (FCO2) vs fractional radiofrequency (FRF) and FCO2 vs FRF plus FCO2 combination in the treatment of acne scars. Twenty-seven patients were included. Scar severity was scored with “Echelle d'évaluation clinique des cicatrices d'acné” (ECCA) by a dermatologist blinded to treatment. FCO2 and FRF were administered to the right and left halves of the patients' faces, respectively, at the first three visits, once a month. At the fourth visit, FCO2 was administered to both sides. Last evaluation was performed 6 months after the last treatment. Mean ECCA scores for both face halves decreased gradually at each visit compared with Visit-1; however, the effect size of decrease was higher in the right half of the face and in terms of gender differences was higher in women for both sides that the difference was more pronounced for the FRF side. There was no statistically significant change in the mean VAS patient satisfaction scores in the following visits compared with Visit-2 on both halves (P >.05). Side effects were similar; but lasted longer in the FCO2 side. Both FCO2 and FRF are effective treatment methods in the treatment of atrophic acne scars. Combining FCO2 to FRF improves patient satisfaction. FRF may achieve better results in women compared with men. To our knowledge the study is unique prospective, controlled clinical study comparing the efficacy of FCO2 and FRF plus FCO2 combination treatments. © 2020 Wiley Periodicals LLC.
URI: https://hdl.handle.net/11499/36926
https://doi.org/10.1111/dth.14444
ISSN: 1396-0296
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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