Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/37285
Title: | Myocarditis and intracardiac thrombus due to Henoch-Schönlein purpura: case report and literature review | Authors: | Yılmaz, Neslihan Yüksel, Selçuk Becerir, Tülay Girişgen, İlknur Ufuk, Furkan Gürses, Dolunay Yılmaz, Münevver |
Keywords: | Cardiac involvement IgA vasculitis Nephritis Prognosis Treatment |
Publisher: | Springer | Abstract: | Cardiac involvement is very rare in patients with Henoch-Schönlein purpura (HSP). In this case study, we present an 8-year-old girl presenting with HSP-induced myocarditis and thrombus in the right atrium and HSP nephritis. To date, 15 cases of HSP-related cardiac involvement have been reported in the PubMed/MEDLINE, Scopus, and Google Scholar databases. These cases, together with our case, are included in this review. We excluded those patients with other rheumatologic diseases (acute rheumatic fever, acute post-streptococcal glomerulonephritis, Kawasaki disease) accompanied by HSP. Three were children and 13 were adults and all were male except our case. This review revealed tachyarrhythmia, chest pain, dyspnea, murmur, and heart failure as the major signs. Cardiac tests, electrocardiogram (ECG), and imaging methods (echocardiography in all patients, cardiac magnetic resonance imaging (MRI) in three, cardiac biopsy in one, and post-mortem necropsy in three) showed that the cardiac involvements were pericardial effusion, intra-atrial thrombus, myocarditis, coronary artery changes, myocardial ischemia, infarction and necrosis, subendocardial hemorrhage, and left ventricular dilatation. Kidney involvement was not observed in three patients. As the treatment, high-dose prednisolone and cyclophosphamide, oral corticosteroid, azathioprine, nadroparin calcium, ACE inhibitors, calcium antagonists, beta-blockers, and diuretics were used. Eleven patients (all three children and eight of the adults) had a complete cardiac recovery. Cardiac involvement in adults was more likely to be fatal. Death (three patients), ischemia, and infarct have been reported only in adults. We suggested that early and aggressive treatment can be life-saving. MRI examination is effective at identifying cardiac involvement. © 2020, International League of Associations for Rheumatology (ILAR). | URI: | https://hdl.handle.net/11499/37285 https://doi.org/10.1007/s10067-020-05317-8 |
ISSN: | 0770-3198 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
File | Size | Format | |
---|---|---|---|
Yılmaz2021_Article_MyocarditisAndIntracardiacThro.pdf | 2.62 MB | Adobe PDF | View/Open |
CORE Recommender
SCOPUSTM
Citations
6
checked on Sep 30, 2024
WEB OF SCIENCETM
Citations
6
checked on Sep 30, 2024
Page view(s)
64
checked on Aug 24, 2024
Download(s)
30
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.