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https://hdl.handle.net/11499/37379
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Şengöz, Tarık | - |
dc.contributor.author | Kılıç-Toprak, Emine | - |
dc.contributor.author | Yaylalı, Olga | - |
dc.contributor.author | Kılıç-Erkek, Özgen | - |
dc.contributor.author | Ozdemir, Y. | - |
dc.contributor.author | Oymak, B. | - |
dc.contributor.author | Şenol, Hande | - |
dc.date.accessioned | 2021-02-02T09:25:34Z | |
dc.date.available | 2021-02-02T09:25:34Z | |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1386-0291 | - |
dc.identifier.uri | https://hdl.handle.net/11499/37379 | - |
dc.identifier.uri | https://doi.org/10.3233/CH-180717 | - |
dc.description.abstract | BACKGROUND: Although radioiodine theraphy (RAIT) is thought to affect blood cells and oxidative stress, hemorheological alterations following dose-dependent RAIT remains unknown. OBJECTIVE: The aim of this study was to determine the effects of RAIT on hemorheological and oxidative stress parameters in patients with differentiated thyroid cancers (DTC). METHODS: Totally 31 DTC patients (mean age 46.32±11.15 years) and 26 healthy controls (mean age 50.50±6.22 years) were included. Venous blood samples were collected from each patient before and after treatment (7th day, 1th month and 6th month). Erythrocyte aggregation-deformability and oxidative stress parameters were determined. p < 0.05 was considered as statistically significant. RESULTS: Erythrocyte deformability of the patients determined at 16.87 and 30 Pascal were significantly lower than healthy individuals. Erythrocyte aggregation index (AI) of the patients was higher, whereas erythrocyte aggregation half-time (t½) was lower compared to control. Erythrocyte deformability values and AI were not significantly different from the pre-and post-radioiodine treatment groups. There was no statistically significant difference between the oxidative stress parameters before and after the treatment. CONCLUSIONS: Patients were in a worse hemorheological condition compared to healthy individuals. After RAIT, RBC deformability and aggregation were not affected and no significant change in oxidative stress parameters was detected. © 2020-IOS Press and the authors. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | IOS Press | en_US |
dc.relation.ispartof | Clinical Hemorheology and Microcirculation | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Differentiated thyroid cancer | en_US |
dc.subject | erythrocyte aggregation | en_US |
dc.subject | erythrocyte deformability | en_US |
dc.subject | I-131 | en_US |
dc.subject | oxidative stress | en_US |
dc.subject | dianisidine | en_US |
dc.subject | ferric ion | en_US |
dc.subject | ferrous sulfate | en_US |
dc.subject | fibrinogen | en_US |
dc.subject | hemoglobin | en_US |
dc.subject | hydrogen peroxide | en_US |
dc.subject | hydroxyl radical | en_US |
dc.subject | iodine 131 | en_US |
dc.subject | levothyroxine sodium | en_US |
dc.subject | oxidizing agent | en_US |
dc.subject | radioactive iodine | en_US |
dc.subject | thyrotropin | en_US |
dc.subject | triacylglycerol | en_US |
dc.subject | Iodine-131 | en_US |
dc.subject | ablation therapy | en_US |
dc.subject | adult | en_US |
dc.subject | antioxidant assay | en_US |
dc.subject | Article | en_US |
dc.subject | blood rheology | en_US |
dc.subject | clinical article | en_US |
dc.subject | colorimetry | en_US |
dc.subject | controlled study | en_US |
dc.subject | differentiated thyroid cancer | en_US |
dc.subject | erythrocyte count | en_US |
dc.subject | female | en_US |
dc.subject | hematocrit | en_US |
dc.subject | histopathology | en_US |
dc.subject | hormone substitution | en_US |
dc.subject | human | en_US |
dc.subject | human tissue | en_US |
dc.subject | leukocyte count | en_US |
dc.subject | male | en_US |
dc.subject | mean corpuscular hemoglobin | en_US |
dc.subject | mean corpuscular volume | en_US |
dc.subject | microcirculation | en_US |
dc.subject | oxidative stress index | en_US |
dc.subject | red blood cell distribution width | en_US |
dc.subject | shear stress | en_US |
dc.subject | thyroid metastasis | en_US |
dc.subject | thyroidectomy | en_US |
dc.subject | total antioxidant level | en_US |
dc.subject | total oxidant level | en_US |
dc.subject | blood | en_US |
dc.subject | case control study | en_US |
dc.subject | metastasis | en_US |
dc.subject | middle aged | en_US |
dc.subject | physiology | en_US |
dc.subject | thyroid tumor | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | Female | en_US |
dc.subject | Hemorheology | en_US |
dc.subject | Humans | en_US |
dc.subject | Iodine Radioisotopes | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Neoplasm Metastasis | en_US |
dc.subject | Oxidative Stress | en_US |
dc.subject | Thyroid Neoplasms | en_US |
dc.title | Hemorheology and oxidative stress in patients with differentiated thyroid cancer following I-131 ablation/metastasis treatment | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 74 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 209 | |
dc.identifier.startpage | 209 | en_US |
dc.identifier.endpage | 221 | en_US |
dc.authorid | 0000-0003-2621-7585 | - |
dc.authorid | 0000-0002-8795-0185 | - |
dc.authorid | 0000-0001-6395-7924 | - |
dc.authorid | 0000-0003-0983-2834 | - |
dc.authorid | 0000-0002-6850-6281 | - |
dc.authorid | 0000-0002-9366-0205 | - |
dc.identifier.doi | 10.3233/CH-180717 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 31884456 | en_US |
dc.identifier.scopus | 2-s2.0-85083041875 | en_US |
dc.identifier.wos | WOS:000525287300010 | en_US |
dc.identifier.scopusquality | Q3 | - |
dc.owner | Pamukkale University | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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