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https://hdl.handle.net/11499/37569
Title: | Prevalence and clinical profile of patients with myocardial infarction with non-obstructive coronary arteries in Turkey (MINOCA-TR): A national multi-center, observational study | Authors: | Kılıç, S. Aydın, G. Çoner, A. Doğan, Y.K. Özlük, Ö.A. Çelik, Y. Ünğan, İ. Taşçanov, Mustafa Düz, Ramazan Polat, Veli Özkan, Hakan Özyaşar, Mehmet Tülüce, Kamil Kurt, Devrim Çetin, Nurullah Gül, Murat İnci, Sinan Çoşkun, Fatma Yılmaz Arı, Hasan Zoghi, Mehdi Ergene, Oktay Türk, Uğur Önsel Yılmaz, Samet |
Keywords: | Coronary angiography Myocardial infarction Myocardial infarction with non-obstructive coronary arteries adult Article cardiovascular risk clinical trial controlled study coronary angiography coronary artery coronary artery bypass graft coronary artery disease diabetes mellitus echocardiography female heart ejection fraction heart infarction heart left ventricle ejection fraction human hyperlipidemia hypertension information processing major clinical study middle aged multicenter study observational study percutaneous coronary intervention prevalence prognosis revascularization risk factor unstable angina pectoris diagnostic imaging male pathophysiology prospective study turkey (bird) Coronary Angiography Coronary Artery Disease Female Humans Male Middle Aged Myocardial Infarction Prevalence Prospective Studies Turkey |
Publisher: | Turkish Society of Cardiology | Abstract: | Objective: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is a relatively new term that is characterized by clinical evidence of MI with normal or near-normal coronary arteries on coronary angiography (QCA). To date, there have been no population-based studies on the prevalence of MINOCA in Turkey. The aim of this nationwide study was to document the prevalence and demographics of MINOCA in a Turkish population. Methods: MINOCA-TR is national, multi-center, prospective, all-comer study that was conducted in 32 hospitals. All consecutive patients who were ?18 years old, diagnosed with MI according to the Third Universal Definition of Myocardial Infarction, and had undergone QCA were included in the study. Patients with stable coronary artery disease, unstable angina pectoris, a history of revascularization, and type 4/5 MI were excluded. Results: A total of 1793 patients who were diagnosed with MI and had undergone QCA were screened between March 2018 and October 2018, of whom 1626 (mean age: 61.5±12.5 years, 70.7% male) were enrolled from 32 centers. The prevalence of MINOCA was 6.7% (n=109) in the overall study population. Compared with non-MINOCA patients, those with MINOCA were younger, had a higher prevalence of the female gender, and had a history of flu. The percentages of current smokers, ST-segment elevated myocardial infarction patients, and those with a history of hypertension, diabetes mellitus, and hyperlipidemia were significantly lower in MINOCA patients (p<0.05, for all). Also, the median left ventricular ejection fraction as seen on echocardiography and the ratio of Killip Class I status at presentation was significantly higher in MINOCA patients than in non-MINOCA patients (p<0.001). Patients with MINOCA received a preload dose of P2Y12 antagonist before QCA less often than non-MINOCA patients (p<0.001). Conclusion: The prevalence of MINOCA in Turkey is 6.7% in patients who were admitted with MI. Also, as compared to non-MINOCA patients, the MINOCA patients were exposed to fewer traditional risk factors of coronary artery disease. (Anatol J Cardiol 2020; 23: 176-82) © 2020 by Turkish Society of Cardiology. | URI: | https://hdl.handle.net/11499/37569 https://doi.org/10.14744/AnatolJCardiol.2019.46805 |
ISSN: | 2149-2263 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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