Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/37569
Title: Prevalence and clinical profile of patients with myocardial infarction with non-obstructive coronary arteries in Turkey (MINOCA-TR): A national multi-center, observational study
Authors: Kılıç, S.
Aydın, G.
Çoner, A.
Doğan, Y.K.
Özlük, Ö.A.
Çelik, Y.
Ünğan, İ.
Taşçanov, Mustafa
Düz, Ramazan
Polat, Veli
Özkan, Hakan
Özyaşar, Mehmet
Tülüce, Kamil
Kurt, Devrim
Çetin, Nurullah
Gül, Murat
İnci, Sinan
Çoşkun, Fatma Yılmaz
Arı, Hasan
Zoghi, Mehdi
Ergene, Oktay
Türk, Uğur Önsel
Yılmaz, Samet
Keywords: Coronary angiography
Myocardial infarction
Myocardial infarction with non-obstructive coronary arteries
adult
Article
cardiovascular risk
clinical trial
controlled study
coronary angiography
coronary artery
coronary artery bypass graft
coronary artery disease
diabetes mellitus
echocardiography
female
heart ejection fraction
heart infarction
heart left ventricle ejection fraction
human
hyperlipidemia
hypertension
information processing
major clinical study
middle aged
multicenter study
observational study
percutaneous coronary intervention
prevalence
prognosis
revascularization
risk factor
unstable angina pectoris
diagnostic imaging
male
pathophysiology
prospective study
turkey (bird)
Coronary Angiography
Coronary Artery Disease
Female
Humans
Male
Middle Aged
Myocardial Infarction
Prevalence
Prospective Studies
Turkey
Publisher: Turkish Society of Cardiology
Abstract: Objective: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is a relatively new term that is characterized by clinical evidence of MI with normal or near-normal coronary arteries on coronary angiography (QCA). To date, there have been no population-based studies on the prevalence of MINOCA in Turkey. The aim of this nationwide study was to document the prevalence and demographics of MINOCA in a Turkish population. Methods: MINOCA-TR is national, multi-center, prospective, all-comer study that was conducted in 32 hospitals. All consecutive patients who were ?18 years old, diagnosed with MI according to the Third Universal Definition of Myocardial Infarction, and had undergone QCA were included in the study. Patients with stable coronary artery disease, unstable angina pectoris, a history of revascularization, and type 4/5 MI were excluded. Results: A total of 1793 patients who were diagnosed with MI and had undergone QCA were screened between March 2018 and October 2018, of whom 1626 (mean age: 61.5±12.5 years, 70.7% male) were enrolled from 32 centers. The prevalence of MINOCA was 6.7% (n=109) in the overall study population. Compared with non-MINOCA patients, those with MINOCA were younger, had a higher prevalence of the female gender, and had a history of flu. The percentages of current smokers, ST-segment elevated myocardial infarction patients, and those with a history of hypertension, diabetes mellitus, and hyperlipidemia were significantly lower in MINOCA patients (p<0.05, for all). Also, the median left ventricular ejection fraction as seen on echocardiography and the ratio of Killip Class I status at presentation was significantly higher in MINOCA patients than in non-MINOCA patients (p<0.001). Patients with MINOCA received a preload dose of P2Y12 antagonist before QCA less often than non-MINOCA patients (p<0.001). Conclusion: The prevalence of MINOCA in Turkey is 6.7% in patients who were admitted with MI. Also, as compared to non-MINOCA patients, the MINOCA patients were exposed to fewer traditional risk factors of coronary artery disease. (Anatol J Cardiol 2020; 23: 176-82) © 2020 by Turkish Society of Cardiology.
URI: https://hdl.handle.net/11499/37569
https://doi.org/10.14744/AnatolJCardiol.2019.46805
ISSN: 2149-2263
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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