Oxyphilic clear cell carcinoma of the ovary: Report of a unique case

Abstract

Clear cell carcinoma (CCC) of the ovary is a rare and easily recognized, malignant tumor, composed of typically polyhedral cells which have distinct cell membranes, and contain abundant clear cytoplasm and eccentric nuclei. They may be associated with endometriosis and often have a poor prognosis. Here, we report a case of bilateral oxyphilic variant CCC of the ovary with widespread metastasis, and peculiar features and differential diagnosis of this rare neoplasm are briefly discussed. In conclusion, clear cell carcinomas must be thought in the differential diagnosis of the ovarian tumors which contain oxyphilic cells

Pamukkale Univ, Sch Med, Dept Obstet & Gynaecol, Denizli, Turkey.