Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4313
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dc.contributor.authorHatip-Al-Khatib, İzzettin-
dc.contributor.authorHatip, F.B.-
dc.contributor.authorYoshimitsu, Y.-
dc.contributor.authorIwasaki, K.-
dc.contributor.authorEgashira, N.-
dc.contributor.authorLiu, A.-X.-
dc.contributor.authorMishima, K.-
dc.date.accessioned2019-08-16T11:33:21Z
dc.date.available2019-08-16T11:33:21Z
dc.date.issued2007-
dc.identifier.issn0951-418X-
dc.identifier.urihttps://hdl.handle.net/11499/4313-
dc.identifier.urihttps://doi.org/10.1002/ptr.2050-
dc.description.abstractThe effects of Toki-shakuyaku-san (TSS) ingredients on acetylcholine (ACh) release in the dorsal hippocampus (DH) were investigated in intact and twice-repeated ischemic rats using in vivo microdialysis-HPLC. Moreover, the effect of TSS on blood flow was investigated in intact rats using laser Doppler flowmetry. TSS at 300 mg/kg p.o. increased ACh and blood flow after 40 min in intact rats. TSS also increased ACh in ischemic rats but to a lesser extent than in intact rats. These results could suggest that TSS-increased ACh and blood flow in DH may contribute in the cognition improving property of TSS. Copyright © 2006 John Wiley & Sons, Ltd.en_US
dc.language.isoenen_US
dc.relation.ispartofPhytotherapy Researchen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcetylcholineen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectBlood flowen_US
dc.subjectHippocampusen_US
dc.subjectMemoryen_US
dc.subjectToki-Shakuyaku-Sanen_US
dc.subjectacetylcholineen_US
dc.subjectherbaceous agenten_US
dc.subjecttoki shakuyaku sanen_US
dc.subjectunclassified drugen_US
dc.subjectanimal modelen_US
dc.subjectarticleen_US
dc.subjectbrain blood flowen_US
dc.subjectChinese medicineen_US
dc.subjectcognitionen_US
dc.subjectcontrolled studyen_US
dc.subjecthigh performance liquid chromatographyen_US
dc.subjecthippocampusen_US
dc.subjectin vivo studyen_US
dc.subjectischemiaen_US
dc.subjectlaser Doppler flowmetryen_US
dc.subjectmaleen_US
dc.subjectmicrodialysisen_US
dc.subjectnonhumanen_US
dc.subjectraten_US
dc.subjectAnimalsen_US
dc.subjectBlood Flow Velocityen_US
dc.subjectBrain Ischemiaen_US
dc.subjectDrugs, Chinese Herbalen_US
dc.subjectLaser-Doppler Flowmetryen_US
dc.subjectMaleen_US
dc.subjectPhytotherapyen_US
dc.subjectPlants, Medicinalen_US
dc.subjectPulsatile Flowen_US
dc.subjectRatsen_US
dc.subjectRats, Wistaren_US
dc.subjectRattusen_US
dc.titleEffect of Toki-Shakuyaku-San on acetylcholine level and blood flow in dorsal hippocampus of intact and twice-repeated ischemic ratsen_US
dc.typeArticleen_US
dc.identifier.volume21en_US
dc.identifier.issue3en_US
dc.identifier.startpage291
dc.identifier.startpage291en_US
dc.identifier.endpage294en_US
dc.authorid0000-0002-9127-6779-
dc.identifier.doi10.1002/ptr.2050-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.pmid17160971en_US
dc.identifier.scopus2-s2.0-33947596095en_US
dc.identifier.wosWOS:000245375400017en_US
dc.identifier.scopusqualityQ2-
dc.ownerPamukkale University-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.grantfulltextnone-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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