Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4417
Title: Cardiovascular diseases in obstructive sleep apnea
Authors: Dursunoglu, Dursun.
Dursunoglu, Neşe.
Keywords: Cardiovascular diseases
CPAP
Hypertension
Metabolic syndrome
Obstructive sleep apnea
acute heart infarction
arousal
breathing disorder
cardiovascular disease
cardiovascular risk
coronary artery disease
diabetes mellitus
diastolic dysfunction
disease association
disease course
disease severity
heart arrhythmia
heart failure
heart left ventricle failure
heart right ventricle failure
heart ventricle function
human
hypercapnia
hypertension
hypoxemia
hypoxia
metabolic syndrome X
morbidity
mortality
obesity
positive end expiratory pressure
pressoreceptor reflex
pulmonary hypertension
review
sleep apnea syndrome
sleep disorder
stroke
sympathetic tone
systolic dysfunction
Cardiovascular Diseases
Humans
Metabolic Syndrome X
Sleep Apnea, Obstructive
Abstract: Obstructive sleep apnea (OSA) affects approximately 5% of women and 15% of men in the middle-aged adults, and associated with adverse health outcomes. Cardiovascular disturbances are the most serious complications of OSA. These complications include heart failure, left/right ventricular dysfunction, acute myocardial infarction, arrhythmias, stroke, systemic and pulmonary hypertension. All these cardiovascular complications increase morbidity and mortality of OSA. Several epidemiologic studies have demonstrated that sleep related breathing disorders are an independent risk factor for hypertension, probably resulting from a combination of intermittent hypoxia and hypercapnia, arousals, increased sympathetic activity, and altered baroreflex control during sleep. Arterial hypertension, obesity, diabetes mellitus and coronary artery disease (CAD) which are independent predictors of left ventricular dysfunction, often have coexistince with OSA. Especially severe OSA patients having diastolic dysfunction might have an increased risk of heart failure, since diastolic dysfunction might be combined with systolic dysfunction. Early recognition and appropriate therapy of ventricular dysfunction is advisable to prevent further progression to heart failure and death. Patients with acute myocardial infarction, especially if they had apneas and hypoxemia without evident heart failure should be evaluated for sleep disorders. So, patients with CAD should be evaluated for OSA and vice versa. Early recognition and treatment of OSA may improve cardiovascular functions. Continuous positive airway pressure (CPAP) applied by nasal mask, is still the gold standard method for treatment of the disease and prevention of complications.
URI: https://hdl.handle.net/11499/4417
ISSN: 0494-1373
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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