In-Vitro Nitric Oxide Scavenging and Anti-Tyrosinase Activity of Two Convolvulus L. Species

Abstract

Convolvulus L. is a member of Convolvulaceae family which have been utilized for their biological activities in folkmedicine. The aim of this study is to investigate the inhibitory effect on tyrosinase activity of two Convolvulus speciesas well as their nitric oxide (NO) scavenging activity potentials. Up to now, no reports have been found on their antityrosinase and NO scavenging activity properties in the literature. C. galaticus and C. phrygius aerial parts wereextracted with methanol and then NO scavenging activity assay was utilized for the assurance of radical scavengingactivity of the extracts. Anti-tyrosinase activity of the extracts was determined using the modified 96-well microplatemethod. The highest NO scavenging and anti-tyrosinase activity were found in C. galaticus as 55.20% and 53.16%,respectively.