Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/45317
Title: Clinical and laboratory factors affecting chronicity in children diagnosed with immune thrombocytopenia
Other Titles: İmmun trombositopenili çocuklarda kronikleşmeyi etkileyen klinik ve laboratuvar faktörler
Authors: Ay, Yılmaz
Sarbay, Hakan
Abstract: Purpose: Immune thrombocytopenia (ITP) is one of the most common hematologic disorders in childhood. Approximately 20-25% of patients with newly diagnosed ITP become chronic. We aimed to investigate the risk factors that may affect chronicity of ITP. Materials and methods: A total of 75 pediatric patients with ITP who were admitted to the Pediatric Hematology Department of Pamukkale University Faculty of Medicine Hospital between January 2013 and July 2018 were included in the study. 17 of the 75 cases were excluded, because 13 of those had lack of data in the system and 4 of those were persistent ITP. The patients’ characteristics such as clinical features, laboratory results, treatment requirements and type of treatment were retrospectively evaluated using the hospital's information system. Results: 46 (79.3%) of the 58 patients with ITP were acute and 12 (20.7%) of those were chronic. The mean age of the patients with acute ITP was 4±3.84 years, while the mean age of the patient with chronic ITP was 9.6±4.6 years. Statistical analysis revealed that children with a diagnosis age greater than 10 years had a significantly higher rate of chronicity. The dominant season in acute cases was spring with 34.8%, while in chronic cases it was summer with 50%. Acute cases were significantly higher in the spring season. 26 of 46 patients with acute ITP (56.5%) and 3 of 12 patients with chronic ITP (25%) were treated with IVIG firstly. Conclusion: We determined that in newly diagnosed patients with ITP who are older 10 years of age and no history of infection may have high risk of chronicity, while the patients diagnosed in the spring and administered IVIG may have less chronicity.
URI: https://hdl.handle.net/11499/45317
https://doi.org/10.31362/patd.695982
ISSN: 1309-9833
1308-0865
Appears in Collections:Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

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