The frequency of fibromyalgia in female patients with impaired fasting blood glucose: crosssectional study

Abstract

Objectives: To assess the frequency of fibromyalgia among women with impaired fasting glucose.Materials and Methods: The sample was selected from the female patients who applied to the InternalMedicine clinic and whose fasting blood glucose level were 100-126 in their routine examination (Group1) andpatients whose fasting blood glucose were less than 100 constituted the control group (Group2). Oral glucosetolerance test (OGTT) has been applied to patients with impaired fasting glucose (IFG) and whose 2nd hourOGTT levels were under 140 has been included. Functional status was assessed by using the FibromyalgiaImpact Questionnaire (FIQ). Pain Location Inventory (PLI), and Symptom Impact Questionnaire (SIQR) wereevaluated for the diagnosis of fibromyalgia.Results: Mean age was 48.99±7.50 in Group1 (n=73) and 47.84±7.92 in Group2 (n=73) with no significantdifference between them. Mean BMI (body mass index) was 30.41±5.01 in Group1 and 28.00±4.61in Group2,this difference was significant (p<0.05). 26% of the patients in Group1, 11% of the patients in Group2 werediagnosed with fibromyalgia and difference was highly significant (p<0.001). Mean FIQ was 44.27±21.98 inGroup1 and 24.95±21.49 in Group2, this difference was also significant (p<0.001). Glucose level was associatedwith PLI (r=0.368, p<0.001), SIQR (r=0.322 p<0.001) and FIQ (r= 0.287, p<0.001).Conclusion: Fibromyalgia is more prevalent in female patients with IFG than in patients with normal fastingglucose levels. Glucose level is associated with both PLI, SIQR and functionality. Although not a clinical disease,IFG is not only a risk factor for development of diabetes but also a risk factor for fibromyalgia in women.