Evaluation of Metabolic and Inflammatory Markers in Patients Undergoing Obesity Surgery

Abstract

Purpose: Obesity is known to improve chronic inflammatory status. It is known that chronic diseases and inflammation regress with weight loss after bariatric surgery. The aim of this study is to evaluate early metabolic and inflammatory changes after laparoscopic sleeve gastrectomy. Materials and methods: The demographic features of the patients who were operated for morbid obesity were evaluated before and after the operation, body mass index, waist circumference, blood leukocyte count, CRP, AST, ALT, GGT levels. Results: Eighty-two patients were included in this study. 21 (25.6%) patients were male and 61 (74.4%) were female. Mean age was 33.7±9.6 (18-64), mean BMI was 42.9±6.1 kg/m2 (32.3-59.4), waist circumference was 126.6±17.7 cm (103-153). Although no significant difference was found between pre-op and post-op mean values, leukocyte, ALT, AST and GGT mean values were found to be lower in the early postoperative period. Conclusion: Chronic inflammation caused by obesity is associated with diabetes, insulin resistance and cancer. Bariatric surgery induced weight loss and anatomical changes can play an important role in healing chronic inflammation. © 2020, Pamukkale University. All rights reserved.