Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/46087
Title: Evaluation of the chest computed tomography and hemogram data in patients with COVID-19: the importance of thymus
Authors: Çakmak, Vefa
Yılmaz, Atakan
Sarı, Tuğba
Çakmak, Pınar
Özen, Mert
Herek, Duygu
Oskay, Alten
Keywords: COVID-19
pneumonia
chest
thymus
lymphocyte
platelet
Respiratory Syndrome
Pneumonia
Wuhan
Ct
Publisher: Scientific And Technological Research Council Turkey
Abstract: Background/aim: To investigate the relationship between imaging findings and peripheral blood cell counts of COVID-19 patients and the degree of thymus fat involution of these patients. Materials and methods: Computed tomography (CT) images of 87 patients with COVID-19 positive through RT-PCR testing were evaluated retrospectively by two radiologists. Ground glass densities and other signs of viral pneumonia were recorded, lung involvement was scored quantitatively. The patients thymus fat involution was graded on CT. Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratios (PLR), lymphocyte and platelet counts were calculated. Imaging findings and degrees of thymus fat involution were compared with laboratory data. Results: Quantitative scoring of lung involvement was calculated at mean 6.63 +/- 4.70 (1-23) for observer 1 and mean 6.55 +/- 4.65 (1-23) for observer 2 (K = 0.824-1.000). Statistical significance was determined between the increase in age and the increase in scores of lung findings (p = 0.003). Lymphocyte count (p = 0.0001) and PLR (p = 0.001) were significantly lower in patients with severe CT involvement. A statistically significantcorrelation was found between increased thymus fat component and presence of COVID-19 lung involvement in CT (r = 0.461). Conclusion: The severity of imaging findings for COVID-19 patients significantly correlates with the degree of fat involution in patients' thymus tissue.
URI: https://doi.org/10.3906/sag-2007-306
https://search.trdizin.gov.tr/yayin/detay/482255
https://hdl.handle.net/11499/46087
ISSN: 1300-0144
1303-6165
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File SizeFormat 
Evaluation of the chest computed tomography and hemogram data in.pdf1.09 MBAdobe PDFView/Open
Show full item record



CORE Recommender

SCOPUSTM   
Citations

7
checked on Dec 14, 2024

WEB OF SCIENCETM
Citations

8
checked on Dec 19, 2024

Page view(s)

74
checked on Aug 24, 2024

Download(s)

30
checked on Aug 24, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.