Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/46148
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dc.contributor.authorSeymen-Karabulut, Gulcan-
dc.contributor.authorGunlemez, Ayla-
dc.contributor.authorGokalp, Ayse Sevim-
dc.contributor.authorHatun, Sukru-
dc.contributor.authorNarter, Fatma Kaya-
dc.contributor.authorMutlus, Mehmet-
dc.contributor.authorKader, Sebnem-
dc.contributor.authorTerek, Demet-
dc.contributor.authorHantas, Deniz-
dc.contributor.authorOkulu, Emel-
dc.contributor.authorKaradeniz, Leyla-
dc.contributor.authorZenciroglu, Aysegul-
dc.contributor.authorOzdemir, Ozmert M. A.-
dc.contributor.authorSarici, Dilek-
dc.contributor.authorCelik, Muhittin-
dc.contributor.authorDemir, Nihat-
dc.contributor.authorTuran, Ozden-
dc.contributor.authorCelik, Kiymet-
dc.contributor.authorKilicbay, Fatih-
dc.contributor.authorUslu, Sinan-
dc.contributor.authorErol, Sara-
dc.contributor.authorErtugrul, Sabahattin-
dc.contributor.authorEr, Ilkay-
dc.contributor.authorCelik, Hasan Tolga-
dc.contributor.authorCetinkaya, Merih-
dc.contributor.authorAkurk-Acar, Filiz-
dc.contributor.authorAslan, Yakup-
dc.contributor.authorTunc, Gaffari-
dc.contributor.authorGuran, Omer-
dc.contributor.authorArisoy, Ayse Engin-
dc.date.accessioned2023-01-09T21:09:38Z-
dc.date.available2023-01-09T21:09:38Z-
dc.date.issued2021-
dc.identifier.issn1308-5727-
dc.identifier.issn1308-5735-
dc.identifier.urihttps://doi.org/10.4274/jcrpe.galenos.2020.2021.0169-
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/521131-
dc.identifier.urihttps://hdl.handle.net/11499/46148-
dc.description.abstractObjective: Late neonatal hypocalcemia (LNH) is a common metabolic problem associated with hypoparathyroidism, high phosphate intake and vitamin D deficiency, often presenting with seizures. In this cross-sectional study, we aimed to evaluate the role of vitamin D deficiency in LNH in Turkey and to describe the characteristics of affected newborns. Methods: Conducted with a cross-sectional design and with the participation of 61 neonatal centers from December 2015 to December 2016, the study included term neonates with LNH (n=96) and their mothers (n=93). Data were registered on the FAVOR Web Registry System. Serum samples of newborns and mothers were analyzed for calcium, phosphate, magnesium, albumin, alkaline phosphatase, intact parathyroid hormone (iPTH) and 25 hydroxyvitamin D [25(OH)D] levels. Results: The median (range) onset time of hypocalcemia was 5.0 (4.0-8.0) days of age, with a male preponderance (60.4%). The median (range) serum 25(OH)D levels of the neonates and their mothers were 6.3 (4.1-9.05) and 5.2 (4.7-8.8) ng/mL, respectively. The prevalence of vitamin D deficiency (<12 ng/mL) was high in both the neonates (86.5%) and mothers (93%). Serum 25(OH)D levels of the infants and mothers showed a strong correlation (p<0.001). While the majority (93.7%) of the neonates had normal/high phosphorus levels, iPTH levels were low or inappropriately normal in 54.2% of the patients. Conclusion: Vitamin D deficiency prevalence was found to be high in LNH. Efforts to provide vitamin D supplementation during pregnancy should be encouraged. Evaluation of vitamin D status should be included in the workup of LNH.en_US
dc.description.sponsorshipKocaeli University Scientific Research Funden_US
dc.description.sponsorshipThis study was supported by Kocaeli University Scientific Research Fund.en_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of Clinical Research In Pediatric Endocrinologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVitamin D deficiencyen_US
dc.subjecthypocalcemiaen_US
dc.subjectinfanten_US
dc.subjectnewbornen_US
dc.subjectLate-Onset Hypocalcemiaen_US
dc.subjectD Supplementationen_US
dc.subjectHigh-Risken_US
dc.subjectPseudohypoparathyroidismen_US
dc.subjectSeizuresen_US
dc.subjectChildrenen_US
dc.subjectRicketsen_US
dc.subjectInfantsen_US
dc.titleVitamin D Deficiency Prevalence in Late Neonatal Hypocalcemia: A Multicenter Studyen_US
dc.typeArticleen_US
dc.identifier.volume13en_US
dc.identifier.issue4en_US
dc.identifier.startpage384en_US
dc.identifier.endpage390en_US
dc.authoridKutman, Hayriye Gözde Kanmaz/0000-0002-3177-9411-
dc.authoridNarter, Fatma/0000-0001-6858-790X-
dc.authoridGUNLEMEZ, AYLA/0000-0003-1492-3861-
dc.authoridKutman, H. Gozde Kanmaz-
dc.identifier.doi10.4274/jcrpe.galenos.2020.2021.0169-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid57192257736-
dc.authorscopusid6602374193-
dc.authorscopusid35605538100-
dc.authorscopusid6701904913-
dc.authorscopusid23095361700-
dc.authorscopusid35339705500-
dc.authorscopusid54395476700-
dc.authorwosidDEMİR, NİHAT/GRY-3625-2022-
dc.authorwosidKutman, Hayriye Gözde Kanmaz/AAH-9681-2021-
dc.authorwosidÇelik, Hasan Tolga/AGK-4959-2022-
dc.authorwosidCetinkaya, Merih/AFP-9671-2022-
dc.authorwosidGUNLEMEZ, AYLA/H-5480-2018-
dc.identifier.pmid34013710en_US
dc.identifier.scopus2-s2.0-85122224644en_US
dc.identifier.trdizinid521131en_US
dc.identifier.wosWOS:000734457400003en_US
dc.identifier.scopusqualityQ2-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairetypeArticle-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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