Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/46183
Title: CAN PLACENTAL HISTOPATHOLOGICAL LESIONS BE A GUIDE TO MATERNAL AND NEONATAL OUTCOMES IN PATIENTS WITH PREECLAMPSIA?
Authors: Atigan, Ayhan
Kilic, Derya
Guler, Tolga
Karakaya, Yeliz Arman
Keywords: Preeclampsia
massive perivillous fibrinoid deposition
syncytial knots
neonatal outcomes
obstetric complications
Terminal Villi
Calcium
Birth
Publisher: Istanbul Univ, Fac Medicine, Publ Off
Abstract: Objective: The aim of this study was to investigate the predictive role of massive perivillous fibrinoid deposition (MPFD), syncytial knots, and accompanying histopathological features of placentas of preeclampsia (PE) on maternal and neonatal outcomes. Matherials and methods: A retrospective clinicopathological study was conducted in a tertiary unit. In the study, 51 pregnant women admitted with PD and 55 normotensive healthy pregnant women matched for age and gestational age were compared. Information regarding clinical characteristics, neonatal findings, and placental properties such as syncytial knots, vascular structure density, placental area, volume, and weight) was retrieved. Results: Massive perivillous fibrinoid deposition, syncytial knots and decreased vessels in terminal villi were significantly frequent in the PE group compared to the controls. However, these histopathological findings were not associated with clinical and neonatal outcomes. Conclusions: Syncytial knot and perivillous fibrin deposition are significant microscopic findings of preeclampsia. However, the presence and amount of fibrin deposition were not correlated with perinatal outcome.
URI: https://doi.org/10.26650/IUITFD.982918
https://search.trdizin.gov.tr/yayin/detay/1116168
https://hdl.handle.net/11499/46183
ISSN: 1305-6441
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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