Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/46202
Title: Frequency of Direct Oral Anticoagulants Usage in Acute Pulmonary Thromboembolism Treatment in Turkey (TUPEDO)
Authors: Tanriverdi, Elif
Tutar, Nuri
Senturk, Aysegul
Bahadir, Ayse
Aksel, Nimet
Yetkin, Nur Aleyna
Karadeniz, Gulistan
Cetin, Nazli
Tabaru, Ali
Yildirim, Binnaz Zeynep
Sen, Hatice Selimoglu
Ozcelik, Neslihan
Ozsari, Emine
Uzer, Fatih
Cicek, Tugba
Esendagli, Dorina
Hocanli, Iclal
Kocak, Nagihan Durmus
Tapan, Utku
Kurt, Bahar
Arinc, Sibel
Kavas, Murat
Sahin, Fusun
Ergun, Dilek
Ucar, Elif Yilmazel)
Kilic, Talat
Gulmez, Inci
Emre, Julide Celdir
Dogan, Deniz
Ozdemir, Fatma
Duger, Mustafa
Alzafer, Suha
Yarar, Esra
Unat, Damla Serce
Salik, Bilge
Keywords: Venous Thromboembolism
Rivaroxaban
Warfarin
Dabigatran
Management
Publisher: Galenos Publ House
Abstract: Background: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and beneficial in terms of bleeding; however, studies that present up-to-date life data are necessary. Aims: To evaluate the frequency of using DOACs, which are prescribed with a limited number of indications in our country, and real-life data results. Study Design: Cross-sectional study Methods: This cross-sectional survey collected the clinical data (history, current treatment, treatment duration, etc.) of patients with pulmonary thromboembolism and who applied to the physician for follow-up between October 15, 2019, and March 15, 2020. The researchers kept the patient records sequentially. Results: Data from 836 patients with acute pulmonary thromboembolism from 25 centers were collected, and DOAC was used in 320 (38.5%) of them. The most preferred DOAC was rivaroxaban (n = 294, 91.9%). DOAC was mostly preferred because it could not provide an effective INR level with warfarin (n=133, 41.6%). Bleeding was observed in 13 (4%) patients. Conclusion: The use of direct oral anticoagulants is becoming almost as widespread as conventional therapy. Real-life data results are important for their contribution to clinical practice.
URI: https://doi.org/10.4274/balkanmedj.galenos.2021.2021-10-19
https://search.trdizin.gov.tr/yayin/detay/1133635
https://hdl.handle.net/11499/46202
ISSN: 2146-3123
2146-3131
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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