Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/46506
Title: | Changes in serum levels of calcitonin gene-related peptide, adiponectin, and ghrelin in pregnant women with gestational diabetes mellitus | Authors: | Can, Ozlem Kosar Cabus, Umit Kabukcu, Cihan Fenkci, Semin Fenkci, Veysel Enli, Yasar Korkmaz, Berker |
Keywords: | adiponectin calcitonin gene-related peptide gestational diabetes mellitus ghrelin Insulin-Resistance Plasma Ghrelin Glucose-Tolerance Amylin Nerves Hyperglycemia Metabolism Receptors Alpha Pathophysiology |
Publisher: | Wiley | Abstract: | Aim This study was designed to determine serum calcitonin gene-related peptide (CGRP) levels and define whether serum CGRP concentration is associated with adiponectin and ghrelin in pregnant women with gestational diabetes mellitus (GDM). Study Design Thirty-six pregnant women with GDM and 43 normal pregnant women without glucose intolerance were evaluated in this study. The serum concentration of CGRP, adiponectin, and ghrelin were measured in two groups at the last trimester of gestation. Main Findings The serum CGRP level in the GDM group was significantly higher than the control group. Serum levels of adiponectin and ghrelin in the GDM group were significantly lower than in the control group. In pregnant women with GDM, there was a significant negative correlation between serum CGRP level and adiponectin level. However, the correlation between maternal serum CGRP levels and ghrelin levels was not significant. Conclusion Our investigation shows that serum CGRP level was significantly higher in pregnant women with GDM in comparison with the control group. These results suggest that CGRP may play a very important role in GDM pathogenesis. | URI: | https://doi.org/10.1111/jog.15016 https://hdl.handle.net/11499/46506 |
ISSN: | 1341-8076 1447-0756 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Show full item record
CORE Recommender
SCOPUSTM
Citations
2
checked on Sep 30, 2024
WEB OF SCIENCETM
Citations
2
checked on Sep 30, 2024
Page view(s)
60
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.