Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/46817
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gavcar, Erdal Gorkem | - |
dc.contributor.author | Basay, Buerge Kabukcu | - |
dc.contributor.author | Avci, Esin | - |
dc.contributor.author | Basay, Omer | - |
dc.date.accessioned | 2023-01-09T21:16:18Z | - |
dc.date.available | 2023-01-09T21:16:18Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0022-3956 | - |
dc.identifier.issn | 1879-1379 | - |
dc.identifier.uri | https://doi.org/10.1016/j.jpsychires.2022.05.030 | - |
dc.identifier.uri | https://hdl.handle.net/11499/46817 | - |
dc.description.abstract | Various opinions have been suggested regarding non suicidal self-injury (NSSI) and pain relationship. Opiorphin is a recently found peptide that inhibits enkephaline-catabolizing enzymes. Analgesia caused by opiorphine has been demonstrated in animal experiments. No studies have examined the relationship between opiorphin and pain sensation until today. We aimed to investigate opiorphine and pain threshold among self-injuring adolescents. Adolescents aged 14-18 years were included in the study. The NSSI group consisted of 37 adolescents diagnosed with NSSI according to DSM-V Section 3, and the non-NSSI group consisted of 36 adolescents without any psychiatric disorder. We measured pain threshold with a pressure sensitive algometer device and analyzed saliva opiorphin levels by ELISA method. Mediation analysis was performed using Process Macro developed by Hayes. NSSI group had statistically significantly higher pain threshold and opiorphin levels than the non-NSSI group. There was a positive correlation between pain threshold values and opiorphin levels in the NSSI group. Also, a positive correlation between opiorphin levels and total cutting episode number was found. We searched for a probable relationship of pain threshold with episode number of each type of NSSI act. Accordingly, a positive correlation with two major act and a negative correlation with two minor act was shown. The opiorphine was found to be a mediator variable in the relationship between the pain threshold and the cutting number. The relationship between opiorphin, pain threshold and cutting number and their mediating effects with each other may highlight the pain-based biological origins of NSSI. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Pergamon-Elsevier Science Ltd | en_US |
dc.relation.ispartof | Journal Of Psychiatric Research | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Opiorphin | en_US |
dc.subject | Pain threshold | en_US |
dc.subject | Cutting number | en_US |
dc.subject | Adolescent | en_US |
dc.subject | Non suicidal self injury | en_US |
dc.subject | Dysregulation | en_US |
dc.subject | Enkephalin | en_US |
dc.subject | Disorders | en_US |
dc.subject | Analgesia | en_US |
dc.subject | Validity | en_US |
dc.title | Relationship between saliva opiorphin levels, pain threshold, and cutting number in adolescents with non suicidal self injury | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 151 | en_US |
dc.identifier.startpage | 611 | en_US |
dc.identifier.endpage | 618 | en_US |
dc.identifier.doi | 10.1016/j.jpsychires.2022.05.030 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57720251300 | - |
dc.authorscopusid | 35736879700 | - |
dc.authorscopusid | 57720105100 | - |
dc.authorscopusid | 37080128600 | - |
dc.identifier.pmid | 35636040 | en_US |
dc.identifier.scopus | 2-s2.0-85131064182 | en_US |
dc.identifier.wos | WOS:000809696400029 | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | Article | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
CORE Recommender
SCOPUSTM
Citations
3
checked on Nov 16, 2024
WEB OF SCIENCETM
Citations
2
checked on Nov 21, 2024
Page view(s)
80
checked on Aug 24, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.