Development of Chitosan-based Films Containing Hypericum perforatum L. and Citrus limon L. as Potential Wound Dressing Materials

Abstract

The objective of this study is to develop chitosan-based films containing Hypericum perforatum L. and/or Citrus limon L. oils and to investigate their suitability as novel wound dressing materials. The morphology of the chitosan-based films were observed by means of employing the scanning electron microscopy (SEM) and the chemical structure characterization was performed via Fourier Transform Infrared Spectroscopy (FTIR). Hypericum perforatum L. and/or Citrus limon L. were successfully incorporated to the chitosan films. Antibacterial, swelling, and mechanical properties of these films were investigated. The antibacterial property was enhanced by incorporating Hypericum perforatum L. and Citrus limon L. oils in the chitosan films. The outcome of the study reveals that the Hypericum perforatum L. and Citrus limon L. incorporated inside chitosan-based films are of great potential wound dressing in the future, because of their good biocompatible, antimicrobial, and physical properties.