Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/47325
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dc.contributor.authorKaragür, Ege Rıza-
dc.contributor.authorAkgün, Şakir-
dc.contributor.authorAkça, Hakan-
dc.date.accessioned2023-01-09T21:23:57Z-
dc.date.available2023-01-09T21:23:57Z-
dc.date.issued2022-
dc.identifier.issn1064-3745-
dc.identifier.urihttps://doi.org/10.1007/978-1-0716-1170-8_17-
dc.identifier.urihttps://hdl.handle.net/11499/47325-
dc.description.abstractMicroRNAs (miRNAs) are 20–24-nucleotide-long noncoding RNAs that bind to the untranslated region (3? UTR) of their target mRNAs. The importance of miRNAs in medicine has grown rapidly in the 20 years since the discovery of them. As the regulatory function of miRNAs on biological processes was discovered, they were advocated to play a role in the underlying mechanisms of human pathogenesis. Functional studies have confirmed that miRNAs are promising in preclinical development through deregulation of genes targeted by miRNAs in many cancer cases. In this chapter, we summarize the miRNAs identified for some specific types of cancer and their functions. Besides, miRNAs function as cancer biomarker and their benefits to diagnosis and treatment of cancer are also discussed. © 2022, Springer Science+Business Media, LLC, part of Springer Nature.en_US
dc.language.isoenen_US
dc.publisherHumana Press Inc.en_US
dc.relation.ispartofMethods in Molecular Biologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomarkersen_US
dc.subjectCanceren_US
dc.subjectCirculating miRNAsen_US
dc.subjectExosomeen_US
dc.subjectmicroRNAsen_US
dc.subjectmicroRNAen_US
dc.subjecttumor markeren_US
dc.subjectlong untranslated RNAen_US
dc.subjectmessenger RNAen_US
dc.subjectmicroRNAen_US
dc.subjectbioinformaticsen_US
dc.subjectbreast canceren_US
dc.subjectcalculationen_US
dc.subjectcancer incidenceen_US
dc.subjectcancer mortalityen_US
dc.subjectcancer prognosisen_US
dc.subjectcancer recurrenceen_US
dc.subjectcancer risken_US
dc.subjectcolorectal canceren_US
dc.subjectendometrium canceren_US
dc.subjectgeneen_US
dc.subjectgene expressionen_US
dc.subjecthumanen_US
dc.subjectlung canceren_US
dc.subjectmelanomaen_US
dc.subjectpancreas canceren_US
dc.subjectpredictionen_US
dc.subjectprostate canceren_US
dc.subjectbiologyen_US
dc.subjectgeneticsen_US
dc.subjectneoplasmen_US
dc.subjectComputational Biologyen_US
dc.subjectHumansen_US
dc.subjectMicroRNAsen_US
dc.subjectNeoplasmsen_US
dc.subjectRNA, Long Noncodingen_US
dc.subjectRNA, Messengeren_US
dc.titleComputational and Bioinformatics Methods for MicroRNA Gene Predictionen_US
dc.typeBook Parten_US
dc.identifier.volume2257en_US
dc.identifier.startpage349en_US
dc.identifier.endpage373en_US
dc.identifier.doi10.1007/978-1-0716-1170-8_17-
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.authorscopusid55968558200-
dc.authorscopusid57190684561-
dc.authorscopusid6602146139-
dc.identifier.pmid34432287en_US
dc.identifier.scopus2-s2.0-85114089726en_US
dc.identifier.scopusqualityQ3-
item.openairetypeBook Part-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
crisitem.author.dept14.03. Basic Medical Sciences-
crisitem.author.dept14.02. Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
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