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https://hdl.handle.net/11499/47351
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DC Field | Value | Language |
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dc.contributor.author | Otar Yener G. | - |
dc.contributor.author | Paç Kısaarslan A. | - |
dc.contributor.author | Ulu K. | - |
dc.contributor.author | Atalay E. | - |
dc.contributor.author | Haşlak F. | - |
dc.contributor.author | Özdel S. | - |
dc.contributor.author | Bozkaya Yücel B. | - |
dc.contributor.author | Gezgin Yıldırım, Deniz | - |
dc.contributor.author | Çakmak, Figen | - |
dc.contributor.author | Öztürk, Kübra | - |
dc.contributor.author | Çakan, Mustafa | - |
dc.contributor.author | Balık, Zeynep | - |
dc.contributor.author | Hasbal Akkuş, Canan | - |
dc.contributor.author | Yıldız, Mehmet | - |
dc.contributor.author | Erat, Tuğba | - |
dc.contributor.author | Çetin, Benhur Şirvan | - |
dc.contributor.author | Yılmaz, Münevver | - |
dc.contributor.author | Bağlan, Esra | - |
dc.contributor.author | Laçinel Gürlevik, Sibel | - |
dc.contributor.author | Atasayan, Vildan | - |
dc.contributor.author | Karadağ, Şerife Gül | - |
dc.contributor.author | Adrovic, Amra | - |
dc.contributor.author | Çağlayan, Şengül | - |
dc.contributor.author | Tanatar, Ayşe | - |
dc.contributor.author | Demirkan, Fatma Gül | - |
dc.contributor.author | Coşkuner, Taner | - |
dc.contributor.author | Akgün, Özlem | - |
dc.contributor.author | Kasap Cüceoğlu, Müşerref | - |
dc.contributor.author | Kavrul Kayaalp, Gülşah | - |
dc.contributor.author | Şahin, Sezgin | - |
dc.contributor.author | Başaran, Özge | - |
dc.contributor.author | Demir, Ferhat | - |
dc.contributor.author | Barut, Kenan | - |
dc.contributor.author | Çiftel, Murat | - |
dc.contributor.author | Gürses, Dolunay | - |
dc.contributor.author | Baykan, Ali | - |
dc.contributor.author | Özsürekçi, Yasemin | - |
dc.contributor.author | Karagöz, Tevfik | - |
dc.contributor.author | Sönmez, Hafize Emine | - |
dc.contributor.author | Bilginer, Yelda | - |
dc.contributor.author | Aktay Ayaz, Nuray | - |
dc.contributor.author | Aydoğ, Özlem | - |
dc.contributor.author | Yüksel, Selçuk | - |
dc.contributor.author | Sözeri, Betül | - |
dc.contributor.author | Kasapçopur, Özgür | - |
dc.contributor.author | Özen, Seza | - |
dc.date.accessioned | 2023-01-09T21:24:04Z | - |
dc.date.available | 2023-01-09T21:24:04Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0172-8172 | - |
dc.identifier.uri | https://doi.org/10.1007/s00296-021-04980-7 | - |
dc.identifier.uri | https://hdl.handle.net/11499/47351 | - |
dc.description.abstract | To compare the clinical and laboratory findings of multisystem inflammatory syndrome in children (MIS-C), patients with Kawasaki disease (KD) and with macrophage activating syndrome due to systemic juvenile idiopathic arthritis (sJIA-MAS) on real-life data. Patients diagnosed with MIS-C, KD, and sJIA-MAS from 12 different centers in Turkey who were followed for at least 6 months were included in the study. Demographic, clinical, and laboratory findings of all patients were analyzed. A total of 154 MIS-C, 59 KD, and 31 sJIA-MAS patients were included. The median age of patients with MIS-C were higher than those with KD while lower than those with sJIA-MAS (8.2, 3, 12 years, respectively). Myalgia (39.6%), cardiac (50.6%), gastrointestinal (72.7%), and neurological (22.1%) involvements were more common in patients with MIS-C compared to others. MIS-C patients had lower levels of lymphocyte (950 vs 1700 cells/µl) and thrombocyte (173,000 vs 355,000 cells/µl) counts and higher pro-BNP (1108 vs 55 pg/ml) levels than KD. Ferritin levels were higher in patients with MIS-C compared to patients with KD while they were lower than patients with sJIA-MAS (440, 170, 10,442 ng/ml, respectively). Patients with MIS-C had a shorter duration of hospitalization than sJIA-MAS (p = 0.02) while they required intensive care unit admission more frequently (55 vs 8 patients, p < 0.001). The median MAS/sJIA score of MIS-C patients was ? 1.64 (? 5.23 to 9.68) and the median MAS/sJIA score of sJIA-MAS patients was ?2.81 ([? 3.79] to [? 1.27]). MIS-C patients displayed certain differences in clinical and laboratory features when compared to KD and sJIA-MAS. Definition of the differences and similarities between MIS-C and the other intense inflammatory syndromes of childhood such as KD and MAS will help the clinicians while making timely diagnosis. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Science and Business Media Deutschland GmbH | en_US |
dc.relation.ispartof | Rheumatology International | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Kawasaki disease (KD) | en_US |
dc.subject | Macrophage activation syndrome | en_US |
dc.subject | Multisystem inflammatory syndrome in children (MIS-C) | en_US |
dc.subject | Systemic juvenile idiopathic arthritis | en_US |
dc.subject | alanine aminotransferase | en_US |
dc.subject | aspartate aminotransferase | en_US |
dc.subject | brain natriuretic peptide | en_US |
dc.subject | D dimer | en_US |
dc.subject | ferritin | en_US |
dc.subject | hemoglobin | en_US |
dc.subject | biological marker | en_US |
dc.subject | ferritin | en_US |
dc.subject | Article | en_US |
dc.subject | child | en_US |
dc.subject | controlled study | en_US |
dc.subject | female | en_US |
dc.subject | ferritin blood level | en_US |
dc.subject | hospitalization | en_US |
dc.subject | human | en_US |
dc.subject | human cell | en_US |
dc.subject | inflammation | en_US |
dc.subject | leukocyte count | en_US |
dc.subject | lymphocyte count | en_US |
dc.subject | macrophage activation syndrome | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | mucocutaneous lymph node syndrome | en_US |
dc.subject | neutrophil count | en_US |
dc.subject | platelet count | en_US |
dc.subject | systemic inflammatory response syndrome | en_US |
dc.subject | systemic juvenile idiopathic arthritis | en_US |
dc.subject | thrombocyte | en_US |
dc.subject | complication | en_US |
dc.subject | juvenile rheumatoid arthritis | en_US |
dc.subject | macrophage | en_US |
dc.subject | macrophage activation syndrome | en_US |
dc.subject | mucocutaneous lymph node syndrome | en_US |
dc.subject | systemic inflammatory response syndrome | en_US |
dc.subject | Arthritis, Juvenile | en_US |
dc.subject | Biomarkers | en_US |
dc.subject | Child | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Ferritins | en_US |
dc.subject | Humans | en_US |
dc.subject | Macrophage Activation Syndrome | en_US |
dc.subject | Macrophages | en_US |
dc.subject | Mucocutaneous Lymph Node Syndrome | en_US |
dc.subject | Systemic Inflammatory Response Syndrome | en_US |
dc.title | Differences and similarities of multisystem inflammatory syndrome in children, Kawasaki disease and macrophage activating syndrome due to systemic juvenile idiopathic arthritis: a comparative study | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 42 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 879 | en_US |
dc.identifier.endpage | 889 | en_US |
dc.identifier.doi | 10.1007/s00296-021-04980-7 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57197869181 | - |
dc.authorscopusid | 6505921333 | - |
dc.authorscopusid | 57222283967 | - |
dc.authorscopusid | 57210705376 | - |
dc.authorscopusid | 57200323933 | - |
dc.authorscopusid | 36492199500 | - |
dc.authorscopusid | 57212533383 | - |
dc.identifier.pmid | 34491393 | en_US |
dc.identifier.scopus | 2-s2.0-85114300271 | en_US |
dc.identifier.scopusquality | Q2 | - |
item.grantfulltext | open | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu |
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Differences and similarities of multisystem.pdf | 616.91 kB | Adobe PDF | View/Open |
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