Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/47516
Title: | Effects of Treatment Adherence on Quality of Life in Hypoparathyroid Patients | Authors: | Anaforoglu, Inan Sancak, Seda Akbas, Emin Murat Oruk, Guzide Gonca Canat, Masum Tezcan, Kadriye Aydin Topbas, Murat |
Keywords: | Hypoparathyroidism Conventional Treatment Treatment Adherence Quality Of Life |
Publisher: | Georg Thieme verlag Kg | Abstract: | Objectives This study aimed to evaluate the current situation of hypoparathyroid patients and to investigate the relationship between treatment adherence and quality of life. Study design Prospective, multicentre study. Methods Adult patients presenting with the diagnosis of hypoparathyroidism to 20 different endocrinology clinics were included. They were receiving conventional therapies for hypoparathyroidism, using calcium, active vitamin D, and magnesium. We collected data on demographic features, disease- and treatment-related information, and results of routine laboratory tests, treatment adherence, and presence of complications. Beck Depression Inventory, Beck Anxiety Inventory, and Short Form-36 quality of life assessments were administered. Results Among the 300 patients studied, 60.7 % were adherent to their treatment, and 34.1 % had complications. Anxiety and depression scores were significantly higher in non- adherent versus treatment-adherent patients (p < 0.001 and p = 0.001, respectively). Most of the domains of quality-of-life scores were also significantly lower in non-adherent patients. Both anxiety and depression scores showed significant, negative correlations with serum calcium and magnesium concentrations ( r = -0.336, p < 0.001 and r = -0.258, p < 0.001, respectively). Conclusions Nearly 40 % of the patients were non-adherent to conventional treatment for hypoparathyroidism, and such patients had higher anxiety and depression scores and poorer quality of life scores. Conventional treatment might not be sufficient to meet the needs of patients with hypoparathyroidism. In addition to seeking new therapeutic options, factors influencing quality of life should also be investigated and strategies to improve treatment adherence should be developed. | Description: | Alphan Uc, Ziynet/0000-0002-0008-2742; Topbas, Murat/0000-0003-4047-4027 | URI: | https://doi.org/10.1055/a-1400-2668 | ISSN: | 0947-7349 1439-3646 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Show full item record
CORE Recommender
SCOPUSTM
Citations
7
checked on Mar 29, 2025
WEB OF SCIENCETM
Citations
6
checked on Mar 31, 2025
Page view(s)
92
checked on Mar 4, 2025
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.