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https://hdl.handle.net/11499/47715
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oner S.Z. | - |
dc.contributor.author | Kaleli I. | - |
dc.contributor.author | Demir M. | - |
dc.contributor.author | Mete E. | - |
dc.contributor.author | Caliskan A. | - |
dc.date.accessioned | 2023-01-09T21:29:44Z | - |
dc.date.available | 2023-01-09T21:29:44Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1022-386X | - |
dc.identifier.uri | https://doi.org/10.29271/jcpsp.2022.12.1605 | - |
dc.identifier.uri | https://hdl.handle.net/11499/47715 | - |
dc.description.abstract | Objective: To evaluate the bacterial and viral causes of central nervous system (CNS) infection by multiplex PCR. Study Design: Descriptive study. Place and Duration of Study: Department of Medical Microbiology, Pamukkale University Faculty of Medicine, Turkey, from March 2016 to December 2021. Methodology: Cerebrospinal fluid (CSF) samples of patients prediagnosed with CNS infection were included in the study. Viral pathogens were detected with the Multiplex real-time PCR panel (FTD Neuro9, Fast Track Diagnostics, Luxembourg) and bacterial pathogens with the multiplex real-time PCR panel (FTD Bacterial Meningitis, Fast Track Diagnostics, Luxembourg). The identification of bacteria growing in samples was done by conventional methods and with the Phoenix™ (Becton Dickinson Diagnostics, USA) automated system. Results: CSF samples of 440 patients were evaluated using multiplex PCR panel. The viral factors included adenovirus (14.2%), human herpes virus 7 (1.5%), varicella zoster virus (1.3%), herpes simplex virus 1 (1.3%), cytomegalovirus (1.3%), Epstein-Barr virus (0.8%), human herpes virus (0.8%), herpes simplex virus 2 (0.3%), varicella zoster virus (0.3%), and parvovirus B19 (0.3%); and bacterial factors included Streptococcus pneumoniae (7.0%) and Neisseria meningitidis (0.9%). The bacterial growth was detected in the CSF culture was 4.9%. Among the growing bacteria, there were six different types that were not found on the multiplex PCR panel. Conclusion: The use of a comprehensive bacterial multiplex PCR panel containing common pathogens will be more effective in pathogen detection. Care should be taken, especially when interpreting the viral Multiplex PCR. © 2022 College of Physicians and Surgeons Pakistan. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | College of Physicians and Surgeons Pakistan | en_US |
dc.relation.ispartof | Journal of the College of Physicians and Surgeons Pakistan | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Bacteria culture | en_US |
dc.subject | Bacterial multiplex PCR | en_US |
dc.subject | Viral multiplex PCR | en_US |
dc.subject | Adenoviridae | en_US |
dc.subject | adult | en_US |
dc.subject | Article | en_US |
dc.subject | bacterial growth | en_US |
dc.subject | bacterium | en_US |
dc.subject | bacterium identification | en_US |
dc.subject | central nervous system infection | en_US |
dc.subject | cerebrospinal fluid analysis | en_US |
dc.subject | Cytomegalovirus | en_US |
dc.subject | descriptive research | en_US |
dc.subject | Epstein Barr virus | en_US |
dc.subject | evaluation study | en_US |
dc.subject | female | en_US |
dc.subject | Herpes simplex virus | en_US |
dc.subject | Herpes simplex virus 2 | en_US |
dc.subject | human | en_US |
dc.subject | Human alphaherpesvirus 1 | en_US |
dc.subject | Human herpesvirus 7 | en_US |
dc.subject | Human parvovirus B19 | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | multiplex polymerase chain reaction | en_US |
dc.subject | Neisseria meningitidis | en_US |
dc.subject | nonhuman | en_US |
dc.subject | Streptococcus pneumoniae | en_US |
dc.subject | Turkey (republic) | en_US |
dc.subject | Varicella zoster virus | en_US |
dc.subject | virus | en_US |
dc.subject | young adult | en_US |
dc.subject | central nervous system infection | en_US |
dc.subject | Epstein Barr virus infection | en_US |
dc.subject | genetics | en_US |
dc.subject | turkey (bird) | en_US |
dc.subject | Bacteria | en_US |
dc.subject | Central Nervous System Infections | en_US |
dc.subject | Epstein-Barr Virus Infections | en_US |
dc.subject | Herpesvirus 4, Human | en_US |
dc.subject | Humans | en_US |
dc.subject | Turkey | en_US |
dc.title | Evaluation of Viral and Bacterial Pathogens in the Central Nervous System Infections with Multiplex PCR | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 32 | en_US |
dc.identifier.issue | 12 | en_US |
dc.identifier.startpage | 1605 | en_US |
dc.identifier.endpage | 1608 | en_US |
dc.identifier.doi | 10.29271/jcpsp.2022.12.1605 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57196044682 | - |
dc.authorscopusid | 6508232943 | - |
dc.authorscopusid | 8657819000 | - |
dc.authorscopusid | 23498029300 | - |
dc.authorscopusid | 56727931300 | - |
dc.identifier.pmid | 36474384 | en_US |
dc.identifier.scopus | 2-s2.0-85143396869 | en_US |
dc.identifier.wos | WOS:000933519600019 | en_US |
dc.identifier.scopusquality | Q3 | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | Article | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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Evaluation of Viral and Bacterial Pathogens.pdf | 150.48 kB | Adobe PDF | View/Open |
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