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https://hdl.handle.net/11499/47773
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Menekse S. | - |
dc.contributor.author | Deniz S. | - |
dc.date.accessioned | 2023-01-09T21:30:00Z | - |
dc.date.available | 2023-01-09T21:30:00Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 2036-6590 | - |
dc.identifier.uri | https://doi.org/10.3855/jidc.15637 | - |
dc.identifier.uri | https://hdl.handle.net/11499/47773 | - |
dc.description.abstract | Introduction: We sought to evaluate secondary infections (SIs) in patients admitted to the intensive care unit (ICU) for COVID-19 with respect to incidence, causative pathogens, and clinical outcomes. Methodology: In this two-centre retrospective study, we analysed 146 patients (96 males, 50 females; median age, 64 years) admitted to the ICU with COVID-19 between March 26 and December 31, 2020. Inclusion criteria were an ICU admission for at least 48 hours and age beyond 18 years. Patients with and without SIs were compared and the impacts of SIs and carbapenem resistance on mortality were analysed. Results: During ICU admission, 84 episodes of SIs developed in 58 patients (39.7%). A total of 104 isolates were recovered, with Gram-negative bacteria most frequent accounting for 74%. At least one carbapenem-resistant pathogen (n = 61) was recovered in 41 patients (70.1%). In multivariate analysis, the use of ECMO and an elevated procalcitonin level were significantly associated with the development of SIs. The mortality rate and the incidence of carbapenem resistance did not differ significantly in COVID-19 patients with and without SIs (p = 0.059 and p = 0.083, respectively). Conclusions: The incidences of SIs and carbapenem resistance among COVID-19 patients were alarming, emphasizing stricter infection control measures in the ICU setting. © 2022 Journal of Infection in Developing Countries. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journal of Infection in Developing Countries | en_US |
dc.relation.ispartof | Journal of Infection in Developing Countries | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Carbapenem resistance | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Intensive care unit infections. | en_US |
dc.subject | Secondary infections | en_US |
dc.subject | carbapenem | en_US |
dc.subject | convalescent plasma | en_US |
dc.subject | procalcitonin | en_US |
dc.subject | steroid | en_US |
dc.subject | tocilizumab | en_US |
dc.subject | carbapenem derivative | en_US |
dc.subject | Acinetobacter baumannii | en_US |
dc.subject | adult | en_US |
dc.subject | adult respiratory distress syndrome | en_US |
dc.subject | aged | en_US |
dc.subject | antibiotic sensitivity | en_US |
dc.subject | APACHE | en_US |
dc.subject | Article | en_US |
dc.subject | bacterium | en_US |
dc.subject | Candida | en_US |
dc.subject | carbapenem resistance | en_US |
dc.subject | coagulase negative Staphylococcus | en_US |
dc.subject | coronavirus disease 2019 | en_US |
dc.subject | days from diagnosis to discharge or mortality | en_US |
dc.subject | duration of central catheter | en_US |
dc.subject | duration of extracorporeal oxygenation | en_US |
dc.subject | duration of invasive ventilation | en_US |
dc.subject | Enterobacter aerogenes | en_US |
dc.subject | Enterococcus | en_US |
dc.subject | Escherichia coli | en_US |
dc.subject | extracorporeal oxygenation | en_US |
dc.subject | female | en_US |
dc.subject | Horowitz index | en_US |
dc.subject | human | en_US |
dc.subject | intensive care unit | en_US |
dc.subject | Klebsiella pneumoniae | en_US |
dc.subject | length of stay | en_US |
dc.subject | male | en_US |
dc.subject | methicillin resistant Staphylococcus aureus | en_US |
dc.subject | methicillin susceptible Staphylococcus aureus | en_US |
dc.subject | microbiological examination | en_US |
dc.subject | mortality rate | en_US |
dc.subject | observational study | en_US |
dc.subject | physical parameters | en_US |
dc.subject | Providencia rettgeri | en_US |
dc.subject | Pseudomonas aeruginosa | en_US |
dc.subject | retrospective study | en_US |
dc.subject | secondary infection | en_US |
dc.subject | septic shock | en_US |
dc.subject | Sequential Organ Failure Assessment Score | en_US |
dc.subject | Serratia marcescens | en_US |
dc.subject | Sphingomona paucimobilis | en_US |
dc.subject | Stenotrophomonas maltophilia | en_US |
dc.subject | adolescent | en_US |
dc.subject | coinfection | en_US |
dc.subject | epidemiology | en_US |
dc.subject | middle aged | en_US |
dc.subject | Adolescent | en_US |
dc.subject | Carbapenems | en_US |
dc.subject | Coinfection | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Intensive Care Units | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Retrospective Studies | en_US |
dc.title | Secondary infections in COVID-19 patients: A two-centre retrospective observational study | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 16 | en_US |
dc.identifier.issue | 8 | en_US |
dc.identifier.startpage | 1294 | en_US |
dc.identifier.endpage | 1301 | en_US |
dc.identifier.doi | 10.3855/jidc.15637 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57200030180 | - |
dc.authorscopusid | 56556385600 | - |
dc.identifier.pmid | 36099372 | en_US |
dc.identifier.scopus | 2-s2.0-85137809567 | en_US |
dc.identifier.wos | WOS:000890137900008 | en_US |
dc.identifier.scopusquality | Q3 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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Secondary infections in COVID-19.pdf | 563.38 kB | Adobe PDF | View/Open |
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