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https://hdl.handle.net/11499/48391
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DC Field | Value | Language |
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dc.contributor.author | Akbudak, İlknur Hatice | - |
dc.contributor.author | Erkek, Özgen Kılıç | - |
dc.contributor.author | Tuzcu, Egem Burcu | - |
dc.contributor.author | Pakyürek, Hilmiye | - |
dc.contributor.author | Küçükatay, Melek Bor | - |
dc.date.accessioned | 2023-01-09T21:37:29Z | - |
dc.date.available | 2023-01-09T21:37:29Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1309-9833 | - |
dc.identifier.issn | 1308-0865 | - |
dc.identifier.uri | https://doi.org/10.31362/patd.839939 | - |
dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/423392 | - |
dc.identifier.uri | https://hdl.handle.net/11499/48391 | - |
dc.description.abstract | Purpose: Some anesthetic drugs are known to have influence on circulation due to hemorheological effects.We aimed to investigate the possible effects of ketamin-xylazine anesthesia, which is extensively used inexperimental animal laboratories on hemorheological parameters.Materials and methods: Adult, male Wistar-Albino rats were divided into two as control (pre-anesthesia)and post-anesthesia (n=17). Ketamin-HCl/Xylazine-HCl (90 mg/kg-10 mg/kg) were injected intraperitoneally.Intracardiac heparinized blood was collected either without anesthesia (control group) or after anesthesia(post-anesthesia group) following the loss of reflexes such as righting, cornea and withdrawal. Erythrocytedeformability was determined by an ektacytometer, while WBV (at shear rates of 38, 76 and 190 s-1) and PV(at 190 s-1 shear rate) at standard (40%) and otolog hematocrit (Hct) were measured via a cone-plate rotationalviscometer.Results: Mean time taken for the disappearance of righting reflex was 4±3.6, corneal reflex 8±6.8 and forwithdrawal reflex 10±6.7 min. 90 mg/kg Ketamin-10 mg/kg Xylazine administration did not affect RBCdeformability, WBV and PV of the rats.Conclusion: These results demonstrate that, use of Ketamin/Xylazine anesthesia may be recommendedespecially when dealing with hemorheological, cardiovascular and hematological parameters. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Pamukkale Tıp Dergisi | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.title | Ketamine/xylazine anesthesia is safe in hemorheological point of view: a preliminary report | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 14 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 444 | en_US |
dc.identifier.endpage | 450 | en_US |
dc.department | PAU | en_US |
dc.identifier.doi | 10.31362/patd.839939 | - |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.trdizinid | 423392 | en_US |
item.grantfulltext | open | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 14.01. Surgical Medicine | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
crisitem.author.dept | 14.03. Basic Medical Sciences | - |
Appears in Collections: | Tıp Fakültesi Koleksiyonu TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection |
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document (6).pdf | 714.76 kB | Adobe PDF | View/Open |
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