Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4873
Title: Impact of obstructive sleep apnea on right ventricular global function: Sleep apnea and myocardial performance index
Authors: Dursunoglu, Neşe
Dursunoglu, Dursun
Kılıç, Mustafa
Keywords: Myocardial performance index, right ventricular
Obstructive sleep apnea
adult
arterial oxygen saturation
arterial oxygen tension
article
body mass
clinical article
controlled study
correlation analysis
demography
diastolic blood pressure
disease severity
female
heart left ventricle ejection fraction
heart performance
heart rate
heart right ventricle failure
heart right ventricle function
heart ventricle function
heart ventricle septum
heart ventricle size
heart ventricle wall
human
hypoxic lung vasoconstriction
lung volume
M mode echocardiography
male
medical assessment
mitral valve
polysomnography
priority journal
sleep apnea syndrome
statistical analysis
systolic blood pressure
tricuspid valve
Adult
Female
Heart Ventricles
Humans
Male
Middle Aged
Organ Size
Reference Values
Sleep Apnea, Obstructive
Ventricular Function, Left
Ventricular Function, Right
Abstract: Background: Obstructive sleep apnea (OSA) is characterized by repetitive upper airway obstructions during sleep, and it might cause cardiovascular complications such as heart failure, arrhythmias, myocardial infarction, systemic and pulmonary hypertension. Objectives: To determine right ventricular diameters and myocardial performance index (MPI) reflecting ventricular global function in uncomplicated OSA patients. Methods: 49 subjects without hypertension, diabetes mellitus, or any cardiac or pulmonary disease referred for evaluation of OSA had overnight polysomnography and complete echocardiographic assessment. According to the apnea-hypopnea index (AHI), subjects were divided into three groups: group 1: control subjects (AHI <5, n = 20), group 2: patients with mild OSA (AHI: 5-14, n = 11), and group 3: moderate-severe OSA (AHI ? 15, n = 18). Right ventricular free wall diameter was measured by M mode, and right ventricular MPI was calculated as (isovolumic contraction time + isovolumic relaxation time)/pulmonary ejection time. Results: There were no differences of age, body mass index, heart rates, systolic and diastolic blood pressures among the groups (p > 0.05). Right ventricular end-diastolic and end-systolic diameters were not statistically different between the groups, and were within normal limits. Also, right ventricular free wall diameter was not significantly different between the groups of control, mild OSA and moderate-severe OSA (6.7 ± 0.9, 6.9 ± 1.0, 7.1 ± 1.1 mm, p > 0.05). Right ventricular diastolic dysfunction was shown only in group 3 patients. Right ventricular MPI was statistically higher in group 3 (0.62 ± 0.18) than in group 2 patients (0.50 ± 0.10), and group 1 patients (0.48 ± 0.08, p < 0.001). Conclusions: It was suggested that patients with moderate-severe OSA had a right ventricular global dysfunction, in addition to the presence of a diastolic dysfunction. Copyright © 2005 S. Karger AG.
URI: https://hdl.handle.net/11499/4873
https://doi.org/10.1159/000085369
ISSN: 0025-7931
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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