Please use this identifier to cite or link to this item:
https://hdl.handle.net/11499/4875
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dursunoglu, Dursun. | - |
dc.contributor.author | Evrengül, Harun. | - |
dc.contributor.author | Polat, B. | - |
dc.contributor.author | Tanrıverdi, Halil | - |
dc.contributor.author | Çobankara, Veli. | - |
dc.contributor.author | Kaftan, Asuman. | - |
dc.contributor.author | Kılıç, Mustafa. | - |
dc.date.accessioned | 2019-08-16T11:38:19Z | - |
dc.date.available | 2019-08-16T11:38:19Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0172-8172 | - |
dc.identifier.uri | https://hdl.handle.net/11499/4875 | - |
dc.identifier.uri | https://doi.org/10.1007/s00296-004-0438-0 | - |
dc.description.abstract | Objective: Changes in lipid profiles, Lp(a) lipoprotein, and acute phase reactants are associated with early atherosclerosis in rheumatoid arthritis (RA). The associations of Lp(a) levels with atherosclerotic disorders, diabetes, RA, and renal diseases suggest that Lp(a) might be involved in autoimmune reactions. Methods: Eighty-seven women with RA diagnosed according to American Rheumatism Association criteria (mean age 45.4±9.4 years) were recruited and 50 healthy women (mean age 44±10.7 years) included as a control group. Serum Lp(a), total cholesterol (TC), triglyceride (TG), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and C-reactive protein levels were analyzed. Results: In the RA and C groups, serum Lp(a) levels were 39.2±20.6 mg/dl and 14.8±9.7 mg/dl, respectively (P<0.001). The TC levels were 188.4±41.8 mg/dl and 185.3±19.3 mg/dl (P>0.05), TG levels were 124.5±50.1 mg/dl and 94.6±24.9 mg/dl (P<0.01), HDL-C levels were 40.0±7.4 mg/dl and 52.8±4.8 mg/dl (P<0.01), and LDL-C levels were 123.4±24.6 mg/dl and 113.3±21.1 mg/dl (P>0.05). While serum CRP levels showed a positive correlation with Lp(a), they correlated negatively with HDL-C levels (r=0.83 and P<0.0001, r=-0.49 and P<0.0001, respectively). It was meaningful that Lp(a) correlated negatively with serum HDL-C level (r=-0.36, P<0.001). Conclusion: It is suggested that higher serum Lp(a), lower HDL-C, higher TG level, and a high ratio of TC/HDL-C might show high risk of atherosclerosis. Inflammation in RA may cause changes in HDL-C and Lp(a) metabolisms. © Springer-Verlag 2004. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Rheumatology International | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Inflammation | en_US |
dc.subject | Lipids | en_US |
dc.subject | Lp(a) lipoprotein | en_US |
dc.subject | Rheumatoid arthritis | en_US |
dc.subject | C reactive protein | en_US |
dc.subject | cholesterol | en_US |
dc.subject | high density lipoprotein cholesterol | en_US |
dc.subject | lipid | en_US |
dc.subject | lipoprotein A | en_US |
dc.subject | low density lipoprotein cholesterol | en_US |
dc.subject | triacylglycerol | en_US |
dc.subject | adult | en_US |
dc.subject | article | en_US |
dc.subject | blood analysis | en_US |
dc.subject | cholesterol blood level | en_US |
dc.subject | controlled study | en_US |
dc.subject | correlation analysis | en_US |
dc.subject | diagnostic procedure | en_US |
dc.subject | female | en_US |
dc.subject | human | en_US |
dc.subject | inflammation | en_US |
dc.subject | lipid blood level | en_US |
dc.subject | lipoprotein blood level | en_US |
dc.subject | major clinical study | en_US |
dc.subject | priority journal | en_US |
dc.subject | protein blood level | en_US |
dc.subject | rheumatoid arthritis | en_US |
dc.subject | triacylglycerol blood level | en_US |
dc.subject | Acute-Phase Proteins | en_US |
dc.subject | Adult | en_US |
dc.subject | Arthritis, Rheumatoid | en_US |
dc.subject | C-Reactive Protein | en_US |
dc.subject | Cholesterol | en_US |
dc.subject | Cholesterol, HDL | en_US |
dc.subject | Cholesterol, LDL | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Hyperlipidemias | en_US |
dc.subject | Lipoprotein(a) | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Triglycerides | en_US |
dc.title | Lp(a) lipoprotein and lipids in patients with rheumatoid arthritis: Serum levels and relationship to inflammation | en_US |
dc.type | Article | en_US |
dc.identifier.volume | 25 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 241 | - |
dc.identifier.startpage | 241 | en_US |
dc.identifier.endpage | 245 | en_US |
dc.authorid | 0000-0002-5232-7078 | - |
dc.authorid | 0000-0002-0705-7726 | - |
dc.identifier.doi | 10.1007/s00296-004-0438-0 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.pmid | 15290086 | en_US |
dc.identifier.scopus | 2-s2.0-20044362604 | en_US |
dc.identifier.wos | WOS:000229070200001 | en_US |
dc.identifier.scopusquality | Q2 | - |
dc.owner | Pamukkale_University | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
crisitem.author.dept | 14.02. Internal Medicine | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection Tıp Fakültesi Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
CORE Recommender
SCOPUSTM
Citations
134
checked on Jul 29, 2024
WEB OF SCIENCETM
Citations
124
checked on Jul 28, 2024
Page view(s)
62
checked on Jul 31, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.