Please use this identifier to cite or link to this item: https://hdl.handle.net/11499/4887
Title: In vitro testing for genotoxicity of 4-CPA by sister chromatid exchange in human lymphocyte culture
Authors: Bağcı, Hüseyin
Bağcı, Gülseren
Açıkbaş, İbrahim
Demir, Göksemin
Keywords: 4-CPA
Genotoxicity
Phenoxy herbicides
Sister chromatid exchange
Tomato
Acetic acid
Cells
Concentration (process)
Food products
Herbicides
Hormones
Plant cell culture
Toxicity
Human lymphocytes
Phenoxyacetic acid
Plant hormones
Genes
4 chlorophenoxyacetic acid
herbicide
phenoxyacetic acid derivative
article
cytogenetics
environmental exposure
food contamination
genotoxicity
health hazard
human
human cell
lymphocyte culture
questionnaire
sister chromatid exchange
tomato
vegetable
Abstract: Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.
URI: https://hdl.handle.net/11499/4887
ISSN: 1300-0144
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Koleksiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collection

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